The QualityStocks Daily Friday, October 27th, 2023

Today's Top 3 Investment Newsletters

QualityStocks(UCLE) $0.1200 +60.43%

MarketClub Analysis(ICU) $1.0200 +28.79%

SmallCapRelations(WRAP) $1.7400 +23.40%

The QualityStocks Daily Stock List

US Nuclear Corp. (UCLE)

QualityStocks, Innovative Marketing, Stock News Now, PoliticsAndMyPortfolio, Wall Street Mover, TopPennyStockMovers, The Online Investor, Pennystockmania, PennyPickGains, MarketBeat and InvestorPlace reported earlier on US Nuclear Corp. (UCLE), and today we highlight the Company, here at the QualityStocks Daily Newsletter.

US Nuclear Corp. is a leader in radiation detection. It develops, manufactures, and also sells radiation detection and measuring equipment internationally. The Company has 100 plus years of experience providing quality Chemical Radiation Detection and Monitoring Instrumentation. US Nuclear is headquartered in Canoga Park, California. The Company lists on the OTC Markets Group’s OTCQB.

US Nuclear has three operating divisions: (Technical Associates (TA)), Overhoff Technology (OTC), and Electronic Control Concepts (ECC). Through these divisions, the Company supplies first-class instrumentation to any industry utilizing radionuclides. These industries include nuclear power plants, national laboratories, government agencies, homeland security, military, and universities and schools. Additionally, industries include research companies, hospitals, medical and dental centers, energy companies, weapons facilities, first responders, local governments, and manufacturing plants.

US Nuclear provides measurement instrumentation for the nuclear energy industry and for developing technological processes including Fusion, Thorium and Molten Salt (MSR) reactor technologies domestically and worldwide. American and International customers include United States Government Agencies, the U.S. Military, Homeland Security, National Laboratories, Universities, Hospitals, nuclear reactor facilities in the USA, China, Canada, South Korea, Argentina, Russia, and others.

US Nuclear also engages in Product Development. Its newest product development is the incorporation of radiation and chemical sensors with drone mounted platforms. Its strategic partnership with FlyCFam UAV provides a complete package to a customer that flies in all-weather, heavy winds, and with a heavy payload. This provides the opportunity to fly many sensors at one time with real-time wireless download.

US Nuclear has a strategic alliance agreement with QYSEA Technology. This agreement is to market, build, sell, as well as service Industrial Underwater Robot Sensor Systems in the United States and globally.

US Nuclear and Grapheton’s implantable bioelectronic sensors can be used to help treat millions of people around the world suffering from mobility problems. Neuroscientists stress there is a large unmet demand to develop implantable sensors and the Artificial Intelligence (AI) required to translate the brain signals into specific commands or actions. US Nuclear has a 40 percent stake in Grapheton.

Grapheton’s innovative, patented bioelectronic implants lead the world in bio-compatibility and longevity. Grapheton has developed various kinds of implantable brain sensors, including ECoG (electrocorticography- monitoring the electrical activity of the brain), spinal stimulation probes, and brain chemical sensors, all of which are already in use at different research centers. Grapheton’s probes are biocompatible, therefore avoiding inflammation. US Nuclear said that it and Grapheton’s brain-machine interface technology has great potential for helping immobilized patients gain mobility once again and perform actions that would have never been possible without this pioneering product.

US Nuclear Corp. (UCLE), closed Friday's trading session at $0.12, up 60.4278%, on 960,525 volume. The average volume for the last 3 months is 126,204 and the stock's 52-week low/high is $0.04525/$0.187.

Aadi Bioscience (AADI)

MarketBeat reported earlier on Aadi Bioscience (AADI), and today we highlight the Company, here at the QualityStocks Daily Newsletter.

Aadi Bioscience Inc. (NASDAQ: AADI) (FRA: 3350) is a clinical-stage biopharmaceutical firm focused on the development and commercialization of precision treatments for genetically defined cancers with alterations in mTOR pathway genes.

The firm has its headquarters in Pacific Palisades, California and was incorporated in November 2007 by Neil Desai. It operates as part of the biotechnology industry, under the healthcare sector. The firm serves consumers in the United States.

The company’s primary goal is to bring transformational therapies to cancer patients with mTOR pathway driver alterations, such as alterations in TSC1 or TSC2 genes, where other mTOR inhibitors have not or cannot be effectively exploited due to problems of pharmacology, effective drug delivery, safety, or effective targeting to the disease site. It has one operating segment, which is the business of developing and commercializing proprietary therapeutics.

The enterprise’s lead drug product, FYARRO, is an mTOR inhibitor indicated for the treatment of adult patients with locally advanced unresectable or metastatic malignant perivascular epithelioid cell tumor (PEComa). FYARRO is a form of sirolimus bound to albumin. Sirolimus is a potent inhibitor of the mTOR biological pathway and inhibits downstream signaling from mTOR, which can promote tumor growth. FYARRO is composed of nanoparticles of sirolimus bound to human albumin with an average size less than 100 nanometers. It has also initiated a tumor-agnostic Phase II study (PRECISION 1) of FYARRO in patients with Tuberous Sclerosis Complex 1 and 2 (TSC1 and TSC2) alterations.

The firm, whose CEO was recently granted an equity award, remains committed to generating additional value for its shareholders.

Aadi Bioscience (AADI), closed Friday's trading session at $4.25, off by 0.700935%, on 81,285 volume. The average volume for the last 3 months is 250,910 and the stock's 52-week low/high is $3.88/$14.13.

Monte Rosa Therapeutics (GLUE)

MarketBeat reported earlier on Monte Rosa Therapeutics (GLUE), and today we highlight the Company, here at the QualityStocks Daily Newsletter.

Monte Rosa Therapeutics Inc. (NASDAQ: GLUE) is a clinical-stage biotechnology firm focused on developing new small molecule precision medicines that use the body’s natural mechanisms to selectively degrade therapeutically relevant proteins.

The firm has its headquarters in Boston, Massachusetts and was incorporated in 2019, on November 21st. It operates as part of the biotechnology industry, under the healthcare sector. The firm serves consumers in the United States and Switzerland.

The company develops a portfolio of novel and molecular glue degraders (MGDs). MGDs are small molecule drugs that employ the body’s natural protein destruction mechanisms to selectively degrade therapeutically relevant proteins. It has developed a degradation platform, called Quantitative and Engineered Elimination of Neosubstrates (QuEEN) to enable its target-centric MGD discovery and development approach and its rational design of MGD product candidates. Its product development on therapeutic targets is backed by biological and genetic rationale discovering and developing novel medicines. The company’s product candidate, MRT-2359, is an orally bioavailable MGD targeting the translation termination factor protein GSPT1. MRT-2359 is in clinical development for potential use in MYC-driven tumors, including metastatic non-small cell lung cancer, small cell lung cancer and neuroendocrine tumors.

The firm’s strategic collaboration with Roche is geared at discovering novel molecular glue degraders targeting cancer and neurological diseases. This will accelerate expansion of its platform and amplify its collective strengths and capabilities, which may in turn open it up to new growth and investment opportunities.

Monte Rosa Therapeutics (GLUE), closed Friday's trading session at $2.78, up 11.2%, on 387,151 volume. The average volume for the last 3 months is 157,050 and the stock's 52-week low/high is $2.44/$10.96.

908 Devices (MASS)

Schaeffer's, StockEarnings and MarketBeat reported earlier on 908 Devices (MASS), and today we highlight the Company, here at the QualityStocks Daily Newsletter.

908 Devices Inc. (NASDAQ: MASS) is a commercial-stage technology firm engaged in the provision of a range of purpose-built handheld and desktop mass spectrometry (MassSpec) devices to interrogate unknown and invisible materials in life sciences research, bioprocessing, industrial biotech, forensics and adjacent markets.

The firm has its headquarters in Boston, Massachusetts and was incorporated in 2012 by Kevin J. Knopp, Steve Araiza, Miller Scott, Michael Jobin, Andrew Bartfay, Christopher D. Brown and Christopher J. Petty. It operates as part of the medical devices industry, under the healthcare sector. The firm primarily serves consumers in the United States.

The company is focused on revolutionizing chemical and biochemical analysis with their simple handheld and desktop devices for critical-to-life applications. It operates in the Americas, Europe, the Middle East, Africa and the Asia Pacific.

The enterprise’s products include Mass Spec, which has been designed for rapid analysis of gas, liquid, and solid materials of unknown identity; MX908, a handheld, battery-powered device; and Rebel, a small desktop analyzer that provides real-time information on the extracellular environment in bioprocesses. It also produces the ZipChip solution, a plug-and-play, high-resolution separation platform that optimizes Mass Spec sample analysis; and Maven and Trace C2, an online device for bioprocess monitoring and control.

The firm was recently awarded $10 million in purchase orders by the U.S. Air Force and Air National Guard Fire and Emergency Services program. It remains focused on better meeting consumer needs, opening itself up to new investments and generating significant value for its shareholders.

908 Devices (MASS), closed Friday's trading session at $5.14, off by 1.9084%, on 82,716 volume. The average volume for the last 3 months is 162,314 and the stock's 52-week low/high is $4.98/$17.71.

Akoya Biosciences (AKYA)

MarketBeat and InsiderTrades reported earlier on Akoya Biosciences (AKYA), and today we highlight the Company, here at the QualityStocks Daily Newsletter.

Akoya Biosciences Inc. (NASDAQ: AKYA) is a life sciences technology firm engaged in the provision of spatial biology solutions focused on transforming discovery and clinical research.

The firm has its headquarters in Marlborough, Massachusetts and was incorporated in 2015 by Nikolay Samusik, Yury Goltsev and Garry Nolan. It operates as part of the medical instruments and supplies industry, under the healthcare sector. The firm serves consumers around the globe.

The company’s mission is to bring context to the world of biology and human health through the power of spatial phenotyping. It has its geographical presence in North America, Europe, the Asia Pacific, the Middle East and Africa. The company generates the majority of its revenue from North America.

The enterprise’s offerings include the PhenoImager platform that enables researchers to visualize, analyze, quantify, and phenotype cells in situ, in fresh frozen or FFPE tissue sections, and tissue microarrays utilizing an automated and high-throughput workflow. It also offers the PhenoCycler instrument, a compact bench-top fluidics system that integrates with a companion microscope to automate image acquisition; PhenoCycler and PhenoImager reagents; and biopharma services. In addition to this, the enterprise offers inForm Tissue, an automated image analysis software package for accurately visualizing and quantifying biomarkers in tissue sections; Phenoptr, which provides functions that consolidate and analyze output tables created by inForm software; phenoptrReports, a software that generates shareable reports and visualizations based on the phenoptr output in an intuitive front-end GUI; and an analysis software partnerships ecosystem.

The company, which is set to announce its latest financial results, remains focused on advancing its formulations and creating additional value for its shareholders.

Akoya Biosciences (AKYA), closed Friday's trading session at $3.13, off by 4.2813%, on 97,373 volume. The average volume for the last 3 months is 123,715 and the stock's 52-week low/high is $3.11/$14.38.

BlueFire Equipment (BLFR)

PennyStocks24, HoleinOneStocks.net, PennyAuthority.com, Leading Stock Alerts, ElitePennyStocks, Penny Lane Reports, QualityStocks, Eastwind Research, AwesomeStockPick, VipStockReports, ExclusiveStockPick, Damn Good Penny Picks, BestStocksDaily, AskSlapper, First Penny Picks, Global Investment Alert, HotStockProfits, Investor News Source, Ascending Stocks, OTCBB Journal, Your Stock Alert, Penny Picks, Penny Stock Newsletter, Penny Stocks Profile, Premier Equity Reports, Pumps and Dumps, Stock Edge, StockMister, The Stock Brainiac, TradeThesePicks, Value Penny Stocks and Lions of Wall Street reported earlier on BlueFire Equipment (BLFR), and today we highlight the Company, here at the QualityStocks Daily Newsletter.

Bluefire Equipment Corp (OTC: BLFR) is a company focused on designing and manufacturing drill bits for use in the exploration and production of oil and gas.

The firm has its headquarters in Houston, Texas and was incorporated in 2008, on June 10th by Anatoli Borrisov, Chet Gutowsky and Tyson Rhode. It operates as part of the apparel manufacturing industry, under the consumer cyclical sector. The firm mainly serves consumers in the United States.

The enterprise is specialized in emerging industries acquisitions with an emphasis on businesses in the industrial space. It sells and leases polycrystalline diamond cutter (PDC) drill bits to drilling contractors and oil and gas companies, as well as provides repair and after sales services. It is also involved in designing, manufacturing and selling its own branded line of fashion and fashion accessories under the label, Pushers Collective, direct to consumers through its retail outlet and website. The company operates a retail store where it sells its own branded line of fashion and accessories. The products offered by the company are headwear, outerwear and shirts, among others.

The enterprise recently announced that it had acquired a 90% stake in Screaming Eagle Partners LLC, a cashflow positive family-owned oil and gas company in the state of Texas. The remaining 10% is owned by Buffalo XXII Operating LLC. It remains focused on expanding its oil and gas asset portfolio and generating significant returns for its shareholders. This may in turn encourage additional investments into the firm and open it up to new growth opportunities.

BlueFire Equipment (BLFR), closed Friday's trading session at $0.345, up 1.4706%, on 232,030 volume. The average volume for the last 3 months is 4.751M and the stock's 52-week low/high is $0.0001/$0.42.

SNDL Inc. (SNDL)

InvestorPlace, Schaeffer's, StockEarnings, StocksEarning, QualityStocks, MarketBeat, Trades Of The Day, Daily Trade Alert, BUYINS.NET, The Street, Kiplinger Today, The Online Investor, StreetInsider, Early Bird, CNBC Breaking News, FreeRealTime, Investopedia, MarketClub Analysis, StockMarketWatch and MarketClub reported earlier on SNDL Inc. (SNDL), and today we highlight the Company, here at the QualityStocks Daily Newsletter.

Cannabis use, whether for medical or recreational purposes, may have adverse effects due to the presence of harmful fungi contaminating the plants, according to a recent peer-reviewed study. The study, published in the “Frontiers in Microbiology” journal, employed data derived from earlier studies, combined with U.S. and international regulations related to the marijuana industry. The researchers examined various contaminants, including mucor, fusarium, penicillium, aspergillus and other fungi capable of infecting cannabis plants and generating mycotoxins.

The findings showed that specific fungi could induce infections in lung and skin tissues, with such infections being more prevalent when marijuana is smoked compared to when it’s ingested. Cancer patients using marijuana to alleviate nausea and enhance their appetite, along with transplant recipients and individuals with type 1 diabetes or HIV, are particularly susceptible to these infections. Additionally, the findings suggest that individuals involved in cannabis harvesting might be at risk.

Lead author Kimberly Gwinn said, “Cannabis and hemp are relatively new crops, and our comprehension of their interactions with pathogens is in its infancy. Many pathogens produce mycotoxins, which are compounds known to have detrimental effects on human health and are closely monitored in other crops.

“In our review, we provide a comprehensive overview of the current literature regarding mycotoxins in cannabis and hemp products,” she continued. “We also highlight the existing research gaps regarding potential mycotoxin contamination in these crops, drawing from insights gained in other crop systems.”

While cannabis research has predominantly focused on the substance and its medicinal applications, there is an imperative need for a more extensive examination of potential health hazards associated with its consumption, according to the study. The authors noted that the absence of standardized human health-risk assessment methodologies applicable to the emerging hemp and cannabis industries has resulted in fewer studies focused on their risk. Additionally, the diverse array of consumer uses for these substances, including medicinal use by patients with specific medical conditions, presents a unique challenge in evaluating and mitigating the health risks associated with contaminants.

The differing cannabis regulations from state to state, particularly in the United States, also pose a challenge to mitigating risks. Notably, fusarium mycotoxins, a common class of fungal contaminants that result in vomiting when consumed, currently lack regulatory oversight in most states.

In light of these discoveries, the authors strongly advise immunocompromised consumers to opt for products that have undergone sterilization, at least until more comprehensive data becomes available. The study’s authors also recommend further exploration and possible regulatory adjustments to safeguard consumers, particularly those with compromised immune systems.

This risk of consuming tainted cannabis products is the reason why it is better for consumers to access their products from licensed companies, such as SNDL Inc. (NASDAQ: SNDL), as opposed to riskier black-market products, which don’t adhere to specific standards.

SNDL Inc. (SNDL), closed Friday's trading session at $1.33, off by 2.2059%, on 2,397,680 volume. The average volume for the last 3 months is 8.081M and the stock's 52-week low/high is $1.25/$3.36.

Coinbase Global Inc. (COIN)

Schaeffer's, InvestorPlace, The Street, Prfmonline, MarketClub Analysis, Greenbackers, QualityStocks, MarketBeat, Kiplinger Today, Investopedia, OTCPicks, SmallCapVoice, Ceocast News, Zacks, The Online Investor, INO Market Report, Early Bird, HotOTC, CoolPennyStocks, Daily Trade Alert, Trades Of The Day, InsiderTrades, StockEgg, Penny Invest, Stock Stars, Stock Rich, StocksEarning, The Wealth Report, Top Pros' Top Picks, Top Gun, BestOtc, The Stock Psycho, CNBC Breaking News, HotShotStocks, StockEarnings, StockHotTips, BullRally, Wealth Daily, MadPennyStocks, FeedBlitz, Energy and Capital, PennyInvest, Smartmoneytrading, PennyTrader Publisher, Summa Money, StockRich, Profit Confidential, Today's Financial News, CryptoCurrencyWire, Stockpalooza, PennyStockVille, AlphaShark Trading, Cabot Wealth, Pennybuster, BloomMoney, Atomic Trades, Eagle Financial Publications, CRWEWallStreet, Dynamic Wealth Report, Dawn Report, Blaque Capital Stocks, Standout Stocks, wyatt research newsletter, WiseAlerts, wealthmintrplus, Wealth Whisperer, TipRanks, StockMister, Stock Traders Chat, Penny Stock Finder, Stock Analyzer, Early Investing, Round Up the Bulls, Penny Stock Rumble, AllPennyStocks, Momentum Traders, MicrocapVoice, Louis Navellier, Green Chip Stocks and Stock Fortune Teller reported earlier on Coinbase Global Inc. (COIN), and today we highlight the Company, here at the QualityStocks Daily Newsletter.

In the ever-changing landscape of decentralized finance and the wider Web3 sphere, security is a top priority. With the constant emergence of new threats, it is crucial to analyze attack patterns to assess risk and reliability. Cointelegraph’s Crypto Hacks database indicates that almost $1 billion worth of crypto was stolen or lost in 2023 alone.

In response to the increasing need for security, a wide range of Web3 security specialists has emerged, from smart contract auditors to decentralized identification solutions, guaranteeing the security of an ever-evolving digital landscape. Yet, a persistent menace continues: the Lazarus Group, a North Korea-affiliated hacking organization. In 2023 alone, the group was accountable for confirmed losses exceeding $291 million, with the latest attack on crypto exchange CoinEx causing losses of almost $55 million.

In another noteworthy instance, the person responsible for the July 30 Curve Finance hack, which caused more than $61 million in crypto losses, has reimbursed Curve Finance and Alchemix Finance for about $8.9 million in cryptocurrency. Surprisingly, the attacker wanted to protect the integrity of the exploited protocols rather than avoid being apprehended. Utilizing a reentrancy issue, the attack impacted multiple pools, including the alETH-ETH pool from Alchemix Finance, the pETH-ETH pool from JPEG and the sETH-ETH pool from Metronome.

Even though the refunded money only makes up 15% of the total amount taken, this event brings to light the complex moral and incentive dynamics in the cryptocurrency industry in the wake of security breaches. This also underscores the need for individual crypto holders and enthusiasts to equip themselves with the skills required to analyze and safeguard their digital assets. Blockchain analysis thus becomes an indispensable investigative tool that makes it possible to examine blockchain transactions and track down the trail of cryptocurrency that has been stolen. It involves several steps, including transaction tracing, address clustering, behavioral analysis and regulatory vigilance, as well as pattern recognition aided by historical data and known attack patterns.

While blockchain analysis stands as one of the best investigators’ essential tools, open-source intelligence (OSINT) complements it, offering a broader perspective on entities and individuals linked to a hack. OSINT employs tools such as Breadcrumbs, Ethective, Tenderly, Nansen and Etherscan aid investigators in gaining a more comprehensive understanding of the situation.

Combining OSINT with blockchain analysis can construct a holistic view of the hack, potentially unmasking the culprits and facilitating the recovery of stolen assets. Major exchanges such as Coinbase Global Inc. (NASDAQ: COIN) have to set up meticulously robust cybersecurity measures so that their millions of users don’t suffer losses occasioned by hackers.

Coinbase Global Inc. (COIN), closed Friday's trading session at $70.78, off by 5.1334%, on 9,010,568 volume. The average volume for the last 3 months is 115,123 and the stock's 52-week low/high is $31.55/$114.43.

Kandi Technologies Group Ltd. (KNDI)

Green Car Stocks, MarketClub Analysis, QualityStocks, InvestorPlace, Schaeffer's, The Street, StockMarketWatch, Hit and Run Candle Sticks, StreetInsider, TraderPower, Alternative Energy, Jason Bond, Greenbackers, GreatStockPix, Wall Street Resources, TradersPro, China Stock Alerts, MarketBeat, BUYINS.NET, Investing Futures, Marketbeat.com, Money Morning, Penny Stock Rumble, ProfitableTrading, SmarTrend Newsletters, StreetAuthority Daily, Trades Of The Day, TradingMarkets, TopStockAnalysts, FeedBlitz, Energy and Capital, Dynamic Wealth Report, DrStockPick, Street Insider, CRWEWallStreet, StockRich, CRWEPicks, CRWEFinance, CoolPennyStocks, ChartAdvisor, Weekly Wizards, BullRally, BestOtc, Barchart, Daily Trade Alert, Stock Traders Chat, Profit Confidential, PennyTrader Publisher, PennyToBuck, PennyStockVille, PennyOmega, PennyInvest, Rick Saddler, SmallCapNetwork, HotOTC, SmallCapVoice, Money and Markets, MadPennyStocks, StockEgg, InvestorsUnderground, Investors Alley, StockHotTips, InvestorGuide, Investor Ideas, INO.com Market Report and Willy Wizard reported earlier on Kandi Technologies Group Ltd. (KNDI), and today we highlight the Company, here at the QualityStocks Daily Newsletter.

Toyota has surpassed Tesla as the top electric vehicle brand in the United States with only one battery electric vehicle (BEV) model in the American market. While Tesla has several best-selling EVs, including the Model 3 and Model Y, Toyota has one — the bZ4X — along with the popular Toyota Prius and RAV4 Prime as its hybrid offerings.

The Japanese automaker is one of the only automakers that hasn’t invested in battery electric vehicles in recent years, focusing instead on hydrogen-powered, plug-in vehicles in select U.S. markets. Toyota has also made significant investments in solid-state batteries, a new kind of EV battery that replaces liquid electrolytes with solid alternatives for greater safety and higher energy density.

Toyota has solidified its place in the auto market and has built a ton of customer goodwill and brand awareness over decades of operations. Even though Toyota essentially has limited alternative energy vehicle models, with its most popular being a hybrid, Toyota presents a more desirable electric vehicle brand compared to Tesla.

A 2023 survey of 6,000 American drivers found that 30% prefer EVs from Toyota and 23% prefer Tesla followed by Honda, GM and Ford at 20%, 15%,and 14% respectively. Even though Tesla essentially pioneered the global electric vehicle industry and has produced several bestselling EVs, consumers hold Toyota in higher regard as an EV brand.

The survey participants cited high prices as a barrier to EV purchase and noted that electric vehicle range and the availability of reliable charging infrastructure also influenced the decision to purchase an electric car. Thanks to its adoption of Tesla’s NACS charging system, which allows Toyota EVs to tap into North America’s network of superchargers, Toyota is basically covered on the charging front.

With the EV and battery-making segments constantly working to develop more efficient EV batteries, Toyota’s advancements in solid-state batteries may allow the Japanese company to make major breakthroughs in EV battery capacity and range. This would allow Toyota to pull ahead of other automakers and even surpass Tesla’s gigacasting in terms of efficiency and speed.

The fact that American consumers regard Toyota as the number one EV brand may be due to the automaker’s reputation for producing quality products. Toyota is extremely keen on quality control throughout the production process and is known for using raw materials of the highest quality regardless of price.

On the other hand, Tesla and other electric vehicle makers often have significant quality control issues. An Initial Quality Study by J.D. Powers from 2022 found that the quality of new electric cars has dropped by 11% year over year. The study noted that supply chain issues and the semiconductor chip shortage have also impacted the build quality of new electric vehicles.

As enterprises such as Kandi Technologies Group Ltd. (NASDAQ: KNDI) start commercializing their novel solid state batteries, EV models could go a lot farther and alleviate the range anxiety that has kept many from making the switch to electric vehicles, resulting in the competition for brand supremacy heating up even more.

Kandi Technologies Group Ltd. (KNDI), closed Friday's trading session at $3.22, off by 1.3783%, on 88,868 volume. The average volume for the last 3 months is 435,509 and the stock's 52-week low/high is $2.22/$4.2699.

Alliance Resource Partners LP (ARLP)

The Online Investor, Zacks, QualityStocks, TradersPro, The Street, MarketBeat, InvestorPlace, Marketbeat.com, MarketClub Analysis, TopStockAnalysts, The Wealth Report, Dividend Opportunities, TheStockAdvisor, MiningNewsWire, StreetAuthority Daily, Money Morning, DividendStocks, The Motley Fool, BUYINS.NET, Early Bird, Market Intelligence Center Alert, The Growth Stock Wire, TraderPower, Investing Daily, Wealth Insider Alert, TheStockAdvisors, TheOptionSpecialist, Rick Saddler, Daily Wealth, SmarTrend Newsletters, Daily Trade Alert, Trading Concepts, Eagle Financial Publications, Daily Markets, FNNO Newsletters, Greenbackers, Insider Wealth Alert, Investment U, Investor Update, Trades Of The Day, PoliticsAndMyPortfolio.com, Louis Navellier, Top Pros' Top Picks, TheTradingReport, TheStreet Offers, Money and Markets, Short Term Wealth, StockEarnings, StreetInsider and Leeb's Market Forecast reported earlier on Alliance Resource Partners LP (ARLP), and today we highlight the Company, here at the QualityStocks Daily Newsletter.

The International Energy Agency (IEA) predicts that global demand for coal, natural gas and oil will peak by 2030 amid an “unstoppable” energy transition. According to the agency, carbon pollution from the three fossil fuels will also peak by the end of the decade, thanks to the proliferation of renewable energy.

The IEA report predicted that there would be close to 10 times more electric cars than there are now by the end of 2030. Renewable energy sources such as wind and solar will also account for nearly one-half of the worldwide energy mix compared to 30% in 2023.

Most nations have pledged to phase out dirty fuels such as coal and oil in favor of cleaner alternatives such as solar to cut down carbon emissions and mitigate global warming. Although dirty fuels now power a large portion of the global economy, demand is sure to drop as nations around the world ramp up investment in clean energy and turn away from fossil fuels.

The IEA notes that reduced economic growth in China will also cause demand for fossil fuels to drop. China is currently the second-largest economy, the largest energy consumer and the largest polluter on the globe. The Asian nation has made significant investments in green energy and has more installed solar panels than the rest of the world combined. Furthermore, China also represents the world’s largest electric vehicle market and currently accounts for more than one-half of global electric vehicle sales.

However, China has hit an inflection point, and the nation’s energy demands are set to peak in the middle of the decade, IEA says. IEA executive director Faith Birol said the green-energy transition is happening globally and it’s only a matter of time before renewable energy powers the world. This will significantly dampen demand for fossil fuels over the next decade as clean energies and alternative energy vehicles overshadow internal combustion engine (ICE) cars.

In the meantime, geopolitical events are causing gold prices around the world to surge higher by the day. The Russia-Ukraine war was the catalyst that caused sweeping energy shortages and soaring prices. but the IEA says the ongoing situation in Gaza may cause oil prices to rise even further.

Global benchmark prices have already risen by close to 7%, and the conflict may impact oil markets in the region, much like the 1973 Yom Kippur war triggered a chain of events that plunged the world into an energy crisis.

Coal companies such as Alliance Resource Partners LP (NASDAQ: ARLP) have a few more years to enjoy the current favorable market conditions before the demand for coal starts a steady decline until it no longer makes business sense to remain in that vertical.

Alliance Resource Partners LP (ARLP), closed Friday's trading session at $22.48, off by 1.8341%, on 466,569 volume. The average volume for the last 3 months is 452,668 and the stock's 52-week low/high is $17.05/$25.47.

Compass Pathways PLC (CMPS)

InvestorBrandNetwork, QualityStocks, InvestorPlace, MarketBeat, Daily Trade Alert, StreetInsider, Schaeffer's, Trades Of The Day, The Street and Prism MarketView reported earlier on Compass Pathways PLC (CMPS), and today we highlight the Company, here at the QualityStocks Daily Newsletter.

Researchers from Sorbonne University have found that ketamine can reduce depression symptoms in patients with treatment-resistant depression (TRD) just four hours after infusion. Compared to healthy controls, patients with TRD reported feeling more optimistic a few hours after ketamine infusion, indicating that the psychedelic may have potent and fast-acting mental health benefits.

Prior studies have suggested that ketamine can alleviate depressive symptoms and reduce suicidal thoughts in some people, but this recent study sought to understand exactly how ketamine delivered its antidepression effects.

Hugo Bottemanne from Sorbonne University’s Paris Brain Institute said several pharmacological studies have shown ketamine has the ability to change how people update their beliefs in the face of new information by disturbing the belief-updating process. He also noted another ketamine study that found that the psychedelic can cause a significant and long-term reduction in depressive beliefs in people with major depressive disorder after just one infusion.

Hugo and his team wanted to see how ketamine infusions affected belief updating in TRD patients and how the resulting cognitive effects of ketamine administration affected its clinical effects. They recruited 56 participants including 30 healthy volunteers and 26 individuals with depression. The group had a mean age of 32.4 years and 52% (29) were male.

The latter group included people diagnosed with bipolar depression or major depressive disorder, who had scored more than 20 on the Montgomery-Åsberg Depression Rating Scale (MADRS) and more than 7 on the Maudsley Staging Method, and who hadn’t responded to a least two trials involving antidepressants.

Individuals with addictive or substance-use disorders as well as neurosurgical, psychiatric or neurological comorbidities, or a history of recreational ketamine use were excluded from the study.

The research team observed treatment-resistant depression patients 24 hours before the initial ketamine infusion, 4 hours after ketamine administration, and 4 hours after the third ketamine infusion, which happened a week after the first infusion.

The researchers found that after a single ketamine infusion, people with treatment-resistant depression could update their beliefs more after receiving good news than bad news compared to healthy controls. Furthermore, ketamine infusion caused a “rapid and significant increase” in MADRS scores only four hours after the infusion.

The Montgomery–Åsberg Depression Rating Scale is a diagnostic questionnaire used to test the severity of depressive episodes in people with conditions such as treatment-resistant depression. Bipolar depression, major depressive disorder and treatment-resistant depression often cause patients to develop a pessimistic worldview that causes them to see themselves, the world around them and the future in a persistently negative light.

By making it easier for depression patients to update their beliefs based on good news, ketamine can open the door to more effective depression treatments with greater long-term efficacy.

With many other companies such as Compass Pathways PLC (NASDAQ: CMPS) looking to develop psychedelic medicines from other hallucinogens, it is only a matter of time before patients diagnosed with treatment-resistant depression and other mental illnesses have a variety of effective psychedelic treatment options to choose from.

Compass Pathways PLC (CMPS), closed Friday's trading session at $5.285, off by 3.2051%, on 345,920 volume. The average volume for the last 3 months is 309,353 and the stock's 52-week low/high is $5.2216/$11.48.

TerrAscend Corp. (TSNDF)

QualityStocks, InvestorPlace and Cabot Wealth reported earlier on TerrAscend Corp. (TSNDF), and today we highlight the Company, here at the QualityStocks Daily Newsletter.

Ohio may soon be the latest state in America to legalize recreational cannabis. Reform activists collected enough signatures for a legalization initiative titled Issue 2, and Ohioans are on track to vote on the measure in November.

Multiple polls have found that most Ohio residents plan to vote in favor of the initiative to legalize and regulate recreational cannabis in the state. For example, a September poll by the Coalition to Regulate Marijuana Like Alcohol found that 55% of voters would “probably” or “definitely” support the recreational cannabis legalization initiative.

Before Ohio potentially launches the latest recreational cannabis market in the country, the state could learn from neighbor Michigan, which legalized recreational marijuana in 2019. Soon after, border towns such as Adrian, Michigan, were home to dispensaries that regularly served customers from Ohio.

Amazing Budz dispensary general manager Chris Jacobson notes that half of his customers drive from Ohio, many of them wearing Ohio State University jerseys. Jacobson says some customers come in search of a sleep aid while others are looking for something to boost their appetites.

Ohio Issue 2 will legalize the cultivation, processing, distribution, sale, purchase, possession, home cultivation and use of cannabis for adults aged 21 years and older. It would allow adults to possess up to 15 grams of cannabis concentrates and up to 2.5 ounces of cannabis while also allowing the cultivation of up to six cannabis plants at home.

Local and state taxes on cannabis sales would be divvied up between social-equity and job programs, addiction treatment and education, funding for dispensary host communities, and administrative and regulatory costs.

If Ohio does legalize recreational cannabis, the state could learn some lessons from Michigan’s adult-use industry as well. This could include the average onboarding process for customers at cannabis dispensaries.

Jacobson says his dispensary serves all adults aged 21 and older regardless of their state of origin and uses state-issued IDs to verify customer identity and age. Like Michigan, Ohio first started with a medical cannabis industry and could copy Michigan’s format of dispensaries selling both recreational and medical cannabis.

For instance, Amazing Budz started out as a medical cannabis dispensary, incorporated adult-use marijuana two years later, and now serves both medical and recreational cannabis customers. Jacobson says the creation of cannabis testing standards reduced the risk of tainted products hitting the market, something that could also benefit the Ohio market and protect Ohioans from consuming contaminated cannabis products.

However, recreational cannabis operators in Ohio will also have to deal with the drawbacks of federal prohibition, such as lack of access to banking services.

If and when Ohio eventually launches its recreational marijuana market, opportunities will open up for many companies to potentially grow to the levels that other cannabis enterprises such as TerrAscend Corp. (TSX: TSND) (OTCQX: TSNDF) have risen to in the years that they have been in operation.

TerrAscend Corp. (TSNDF), closed Friday's trading session at $1.51, off by 6.5594%, on 207,934 volume. The average volume for the last 3 months is 145,795 and the stock's 52-week low/high is $1.00/$2.50.

The QualityStocks Company Corner

CNS Pharmaceuticals Inc. (NASDAQ: CNSP)

The QualityStocks Daily Newsletter would like to spotlight CNS Pharmaceuticals Inc. (NASDAQ: CNSP).

Researchers from Stanford Medicine have found that lung cancer cells can spread to the brain and hide from the immune system by pretending to be "baby neurons." After originating in the lungs, these cancer cells can metastasize into the brain and avoid detection by convincing neural cells that they're juvenile neurons through the secretion of a certain chemical signal. These cancer cells secrete a chemical message/signal that is ubiquitous during times of brain development, which attracts brain cells called astrocytes to the cells. This chemical signal encourages the astrocytes to secrete other chemical signals that protect the lung cancer cells and allow them to thrive, making it nigh impossible for the immune system to spot these cancer cells and strike them down. However, physicians may be able to slow down or even stop the proliferation of brain metastasis of small lung cancer cells by blocking this chemical signal and depriving lung cancer cells in the brain of optimal growth conditions. With brain metastasis of small cell lung cancers currently accounting for around 10% to 15% of all forms of lung cancers, such a treatment would aid plenty of cancer patients across the country. Small-cell lung cancer metastasizes into the brain with such regularity that roughly 15% to 20% of people with the condition already have cancer cells in their brains by the time they are diagnosed. Plenty of research resources are being spent by other entities such as CNS Pharmaceuticals Inc. (NASDAQ: CNSP) to investigate promising drug candidates for treating various brain cancers. It is only a matter of time before options with superior clinical outcomes hit the shelves.

CNS Pharmaceuticals Inc. (NASDAQ: CNSP) is a clinical stage biotechnology company specializing in the development of novel treatments for primary and metastatic cancers of the brain and central nervous system.

The company was founded in 2017 and is headquartered in Houston, Texas.

Organ Targeted Therapeutics

The company’s lead drug candidate, Berubicin, is proposed for the treatment of glioblastoma multiforme (“GBM”), an aggressive and incurable form of brain cancer. Berubicin also has potential to treat other central nervous system malignancies. Based on limited clinical data, Berubicin appears to be the first anthracycline to cross the blood brain barrier in the adult brain, and it was the subject of a successful Phase 1 study which found the MDT and produced efficacy data as well.

CNS holds a worldwide exclusive license to the Berubicin chemical compound. The company has acquired all requisite data and know-how from Reata Pharmaceuticals Inc. related to a completed Phase I clinical trial of Berubicin in malignant brain tumors. In this trial, 44% of patients experienced a statistically significant improvement in clinical benefit. In 2017, CNS entered into a collaboration and asset purchase agreement with Reata.

CNS intends to explore the potential of Berubicin to treat other diseases, including pancreatic and ovarian cancers and lymphoma. The company is also examining plans to develop combination therapies that include Berubicin.

CNS estimates that more than $25 million in private capital and grants were invested in Berubicin prior to the company’s $9.8 million IPO in November 2019.

CNS intends to submit an IND for Berubicin during the fourth quarter of 2020 and expects to commence a Phase II clinical trial of Berubicin for the treatment of GBM in the U.S. in Q1 2021. A sub-licensee partner was awarded a $6 million EU/Polish National Center for Research and Development grant to undertake a Phase II trial of Berubicin in adults and a first-ever Phase I trial in pediatric GBM patients in Poland in 2021.

The company’s second drug candidate, WP1244, is a novel DNA binding agent licensed from the MD Anderson Cancer Center. In preclinical studies, WP1244 proved to be 500-times more potent than the chemotherapeutic agent, daunorubicin, in inhibiting tumor cell proliferation. The company has entered into a sponsored research agreement with the MD Anderson Cancer Center to further the development of WP1244.

CNS Pharmaceuticals recently engaged U.S.-based Pharmaceutics International Inc. and Italian BSP Pharmaceuticals SpA for the production of the Berubicin drug product. The company has implemented a dual-track manufacturing strategy to mitigate COVID-19-related risks, diversify its supply chain and provide for localized availability of Berubicin. CNS has already completed synthesis of Berubicin’s active pharmaceutical ingredient (API) and has shipped the API to both manufacturers in order to prepare an injectable form of Berubicin for clinical use.

Global Brain Tumor Therapeutics Market

The high recurrence rate of malignant brain tumors is due to reappearance of focal masses, indicating that a sub-population of tumor cells in these cancers may be insensitive to current therapies and may be responsible for reinitiating tumor growth. This necessitates the development of newer drugs in the market that demonstrate greater efficacy in treating such aggressive cancers.

A global increase in neurological disorders has placed increased attention on cancers of the brain over the past decade. Neurological disorders are becoming one of the most prevalent types of disorders, due to longer life expectancy, greater exposure to infection and an increasingly sedentary lifestyle. Because few treatments for primary and metastatic cancers of the brain exist, costs are high and have acted as a restraint for the brain tumor therapeutics market.

Despite progress in surgery, radiotherapy and chemotherapeutic strategies, effective treatments for brain cancer are limited by a lack of specific therapies for the brain and the difficulty in transporting therapeutic compounds across the blood brain barrier. Therefore, there is a significant need for novel and effective therapeutic drugs and strategies that prolong survival and improve quality of life for brain tumor patients.

Several companies are making significant investments into R&D, which is expected to bring more treatment options to the market in the near future. Industry reports consistently project continued growth in the market.

One report estimates that the global brain tumor therapeutics market will reach a valuation of $2.74 billion in 2023, with the market expected to register a CAGR of 11% during the forecast period from 2018 to 2023. Another report projects that the global brain tumor therapeutics market will reach $3.4 billion by 2025, up from $2.25 billion in 2019 (http://nnw.fm/eDUjp).

Management Team

John M. Climaco is the CEO of CNS Pharmaceuticals. For 15 years, Climaco has served in leadership roles for a variety of health care companies. Recently, Climaco served as the Executive Vice President of Perma-Fix Medical S.A, where he managed the development of a novel method to produce Technitium-99. Climaco also served as President and CEO of Axial Biotech Inc., a DNA diagnostics company. In the process of taking Axial from inception to product development to commercialization, Climaco forged strategic partnerships with Medtronic, Johnson & Johnson and Smith & Nephew.

Christopher Downs, CPA, is the company’s Chief Financial Officer. Downs previously served as Interim Chief Financial Officer and Executive Vice President of InfuSystem Holdings Inc. (NYSE: INFU), a supplier of infusion services to oncologists in the United States. Downs holds a Bachelor of Science from the United States Military Academy at West Point, an MBA from Columbia Business School and a Master of Science in Accounting from the University of Houston-Clear Lake.

Dr. Donald Picker is the Chief Scientific Officer of CNS. Picker has over 35 years of drug development experience. Prior to joining CNS, Picker worked at Johnson Matthey, where he was responsible for the development of Carboplatin, one of the world’s leading cancer drugs, which was acquired by Bristol-Myers Squibb with annual sales of over $500 million. In addition, he oversaw the development of Satraplatin and Picoplatin, third-generation platinum drugs currently in late-stage clinical development.

Sandra L. Silberman, M.D., Ph.D., is the Chief Medical Officer of CNS Pharmaceuticals. Silberman is a hematologist/oncologist who earned her B.A., Sc.M. and Ph.D. from the Johns Hopkins University School of Arts and Sciences, School of Public Health and School of Medicine, respectively, and her M.D. from Cornell University Medical College. She then completed both a clinical fellowship in hematology/oncology and a research fellowship in tumor immunology at the Brigham & Women’s Hospital and the Dana Farber Cancer Institute in Boston, Massachusetts. Silberman has played key roles in the development of many drugs, including Gleevec(TM), for which she led the global clinical development at Novartis. Silberman advanced several original, proprietary compounds into Phases I through III during her work with leading biopharmaceutical companies, including Bristol-Myers Squibb, AstraZeneca, Imclone and Roche.

CNS Pharmaceuticals Inc. (NASDAQ: CNSP), closed Friday's trading session at $1.89, off by 4.5455%, on 119,168 volume. The average volume for the last 3 months is 29,993 and the stock's 52-week low/high is $0.6105/$6.597.

Recent News

Scinai Immunotherapeutics Ltd. (NASDAQ: SCNI)

The QualityStocks Daily Newsletter would like to spotlight Scinai Immunotherapeutics Ltd. (NASDAQ: SCNI).

Scinai will exhibit at the upcoming CPHI Barcelona event, showcasing its CDMO services

The company expanded into the CDMO business earlier this year, operating under the banner Scinai Bioservices

Scinai's boutique end-to-end CDMO business division serves pharmaceutical, biotech, and alternative protein food tech companies with pilot and clinical process development and cGMP manufacturing

Scinai intends to serve small biotech companies who require CDMO services with superior value compared to large, multinational CDMO companies

Scinai will also exhibit at the upcoming BIO-Europe conference in Munich

Scinai Immunotherapeutics (NASDAQ: SCNI), a biotechnology company focused on developing, manufacturing, and commercializing innovative immunotherapeutic products, will be showcasing its Contract Development and Manufacturing Organization ("CDMO") services at CPHI Barcelona, a premier three-day event that brings together pharmaceutical professionals, industry leaders, and businesses to advance human health. The event is scheduled for October 24 to 26, 2023, at Fira Barcelona Gran Via, Spain (https://ibn.fm/veEp4).

Scinai Immunotherapeutics Ltd. (NASDAQ: SCNI) is a biotechnology company focused on developing, manufacturing, and commercializing innovative immunotherapeutic products primarily for the treatment of infectious diseases and autoimmune diseases.

In collaboration with the prestigious Max Planck Institute for Multidisciplinary Sciences (MPG) and the University Medical Center Göttingen (UMG), both in Germany, Scinai is developing a pipeline of innovative nanosized antibody (NanoAb) therapies addressing diseases underserved by current treatments and with large and growing markets, such as COVID-19, asthma and psoriasis.

NanoAbs, also known as VHH-antibodies or Nanobodies, are alpaca-derived nanosized antibodies that exhibit multiple significant competitive advantages over existing antibody therapies, including stability at high temperatures, superior binding affinity, more effective and convenient routes of administration and efficient production. Scinai is uniquely positioned to advance nanosized antibody innovation from R&D through commercialization.

The company’s highly experienced and successful pharmaceutical industry leadership team includes former senior executives from Novartis, GSK and Bristol-Myers Squibb.

Since its founding, Scinai has executed eight clinical trials, including a seven-country, 12,400-participant Phase 3 trial of a prior influenza vaccine candidate, and it built, owns and operates a 20,000 sq. ft. state-of-the-art GMP biologics manufacturing facility housing its laboratories, production facilities and offices.

Lead Candidate: Inhaled COVID-19 NanoAb

In December 2021, Scinai signed definitive agreements with the Max Planck Society – parent organization of the Max Planck Institute for Multidisciplinary Sciences– and the UMG to enter a strategic collaboration for the development and commercialization of innovative COVID-19 NanoAbs.

The company is planning a rapid development path that leverages its expertise and capabilities in biological drug development and manufacturing. Scinai anticipates preclinical proof-of-concept results for an inhaled COVID-19 NanoAb by the end of 2022, with initial Phase 1/2a human clinical trial results expected in 2023.

The intended inhaled mechanism of delivery of Scinai’s COVID-19 NanoAb formulation may serve as a significant differentiator when compared to approved monoclonal antibodies, which are injected. Inhaled delivery has shown to be cheaper, more convenient and likely safer for patients and providers.

NanoAb Pipeline: Psoriasis, Asthma and More

The COVID-19 NanoAb development agreement is part of a broader five-year research collaboration agreement signed in March 2022 covering discovery, development and commercialization of NanoAbs for several other disease indications with large market medical needs, including asthma, psoriasis, macular degeneration and psoriatic arthritis.

Scinai has an exclusive worldwide license for development and commercialization of COVID-19 NanoAbs and exclusive options for similar worldwide licenses for NanoAbs for the above mentioned additional large market disorders currently underserved by approved therapeutic antibodies.

Academic research teams from MPG and UMG have verified strong affinity by the new NanoAbs to their biological target molecules and high thermostability. They have also demonstrated strong neutralization by several NanoAb candidates of their respective target molecules. Neutralization studies of the other NanoAbs are expected to begin later in 2022.

Based on the promising results, Scinai will focus development efforts beginning with the following NanoAbs:

  • NanoAbs targeting IL-17 as drug candidates for the potential treatment of psoriasis and psoriatic arthritis
  • NanoAbs targeting IL-13 and NanoAbs targeting TSLP as drug candidates for the potential treatment of asthma

These are conditions for which the antibody target is validated by existing treatments and the mechanism of action is well understood. Both represent large medical needs and growing markets. Scinai anticipates preclinical proof-of-concept for at least one of these NanoAbs in 2023. This is in addition to the aforementioned human clinical Phase 1/2a for the inhaled COVID-19 NanoAb therapy, which is also anticipated in 2023.

CDMO Services

While NanoAb pipeline development is Scinai’s core focus, the company also offers its cGMP manufacturing facility, aseptic fill and finish suite, laboratories and experienced professionals for contract development and manufacturing organization (CDMO) services. This offering is designed to keep the Scinai team abreast of the latest industry developments and trends while building experience and generating revenue to support the company’s NanoAb pipeline development.

Market Opportunity

COVID-19 treatment, target of the company’s lead NanoAb therapy candidate, had an estimated market size of $22 billion in 2021.

Future Scinai drug candidates will target conditions with large markets growing at attractive CAGRs.

The global asthma treatment market was valued at $18.08 billion in 2019 and is projected to reach $26.01 billion by 2027, exhibiting a CAGR of 4.5% during the forecast period, according to Fortune Business Insights. The research firm predicts that the global psoriasis treatment market will grow from $26.37 billion in 2022 to $47.24 billion by 2029, exhibiting a CAGR of 8.7% over the forecast period.

Management Team

Amir Reichman is Scinai’s CEO. He previously was Head of Global Vaccines Engineering Core Technologies at GSK Vaccines in Belgium. Prior to that, he held leadership roles at Novartis Vaccines’ Global Vaccines Supply Chain Management organization. He was the first employee of NeuroDerm Ltd., a company focused on transdermal drug delivery, and served as Senior Scientist until his departure in 2009. He earned a M.Sc. in Biotechnology Engineering from Ben-Gurion University and an MBA in Finance and Health Care Management from the University of Pennsylvania’s Wharton School.

Tamar Ben-Yedidia, Ph.D., is Chief Science Officer at Scinai. She has more than 30 years of experience in immunology, with specific expertise in the development of vaccines. She began her career with Biotechnology General Ltd., working on development of a recombinant Hepatitis-B vaccine. She later joined the Weizmann Institute of Science, working on the design of a peptide-based vaccine against several pathogens. She is widely published, with numerous refereed articles and invited reviews in various scientific journals. She received her Ph.D. from the Weizmann Institute.

Elad Mark is COO at Scinai. He has over 15 years of biotechnology industry experience encompassing diverse project stages including feasibility studies, conceptual and detailed design, commissioning, qualification and process validation. Prior to joining Scinai, he led Novartis’s $800 million investment in a biologics facility in Singapore. With Biopharmax and Antero, both global pharmaceutical engineering companies, he successfully led projects in Israel, China and Singapore. He holds a BSc. in Engineering from the Afeka Tel Aviv Academic College of Engineering and an MBA from the Open University of Israel.

Uri Ben-Or is CFO at Scinai. He has served as CFO with public life science companies traded on the TASE, OTC and Nasdaq. Ben-Or provides his services to Scinai through CFO Direct, a company he founded and for which he serves as CEO. He served as the VP of Finance of Glycominds, a leading biotechnology company, and as CFO of a spin-off from Telrad Networks. He also served as a Corporate Controller at Menorah Capital Markets and as an Auditor at PWC. He holds a B.A. in Business from the College of Administration, an MBA from Bar-Ilan University, and is a CPA.

Scinai Immunotherapeutics Ltd. (NASDAQ: SCNI), closed Friday's trading session at $0.6201, off by 4.6%, on 13,306 volume. The average volume for the last 3 months is and the stock's 52-week low/high is $6.597/$.

Recent News

InMed Pharmaceuticals Inc. (NASDAQ: INM)

The QualityStocks Daily Newsletter would like to spotlight InMed Pharmaceuticals Inc. (NASDAQ: INM).

InMed Pharmaceuticals (NASDAQ: INM) is a leader in the pharmaceutical research, development, manufacturing and commercialization of rare cannabinoids and cannabinoid analogs. The company today announced that it has closed its offering for the issuance and sale of 3,012,049 pre-funded warrants and preferred investment options to purchase up to an aggregate of 3,012,049 common shares, at a purchase price of $0.83 per pre-funded and associated preferred investment option, in a private placement priced at-the-market under Nasdaq rules. Per a previously announced definitive agreement with respect to certain of its outstanding preferred investment options issued in November 2022 and exercisable for 3,272,733 common shares, in the aggregate, the holders of such outstanding preferred investment options have exercised such investment options for cash at a reduced exercise price of $0.83 per share, in exchange for unregistered new preferred investment options to purchase up to 6,545,466 common shares. InMed secured approximately $5.2 million in aggregate gross proceeds, from which it intends to use the net proceeds to continue pipeline development of its pharmaceutical drug candidates, support commercial sales of rare cannabinoids through its subsidiary BayMedica LLC, and for general working capital purposes. H.C. Wainwright & Co. acted as the exclusive placement agent for the offerings.

To view the full press release, visit https://ibn.fm/pw3Zp

InMed Pharmaceuticals Inc. (NASDAQ: INM) is a global leader in the manufacturing and clinical development of rare cannabinoids. InMed is a clinical stage company developing cannabinoid-based pharmaceutical drug candidates, as well as manufacturing technologies for pharmaceutical-grade rare cannabinoids.

The company is dedicated to delivering new therapeutic alternatives to treat conditions with high unmet medical needs. The company is also developing a proprietary manufacturing technology to produce pharmaceutical-grade rare cannabinoids in the lab and has recently announced an LOI to acquire a leading rare cannabinoid manufacturer.

Research and Technology

There are more than 100 rare cannabinoids found in only trace amounts in the cannabis plant, together making up less than 1% of the plant’s biomass. InMed is initially focused on the therapeutic benefits of cannabinol (CBN) in diseases with high unmet medical need. Preclinical studies of CBN demonstrated an excellent safety profile and showed CBN has potential for therapeutic benefit over other cannabinoids such as tetrahydrocannabinol (THC) and cannabidiol (CBD).

Evidence suggests there may be great therapeutic potential in rare cannabinoids. Each has a specific chemical structure, and different cannabinoids have been observed to have distinct physiological properties in humans, including therapeutic potential for specific diseases as well as unique safety profiles. CBN is the active pharmaceutical ingredient (API) in InMed’s two lead programs for dermatological and ocular diseases.

InMed’s most advanced compound, INM-755, is a CBN topical cream under clinical development for the treatment of epidermolysis bullosa, a severe genetic skin disorder. To date, INM-755 has been evaluated in two Phase 1 clinical trials in healthy volunteers. InMed has filed Clinical Trial Applications in several countries as part of a global Phase 2 clinical trial of INM-755 (cannabinol) cream in epidermolysis bullosa. Responses from the National Competent Authorities and Ethics Committees are expected throughout the summer of 2021.

InMed is also involved in developing INM-088, an ocular CBN formulation being researched for the treatment of glaucoma, the second leading cause of blindness in the developed world. InMed is currently evaluating several formulations to deliver CBN into the eye to address issues of dosing frequency, side effects and treatment penetration. INM-088 is being designed for topical delivery to the eye. This localized delivery results in very little drug being absorbed or migrating into the bloodstream, thus minimizing potential adverse side effects. INM-088 shows promise to reduce intraocular pressure and provide neuroprotection of the eye.

Manufacturing

The limited availability of rare cannabinoids like CBN makes them economically impractical to extract directly from the plant for pharmaceutical use. InMed is developing IntegraSyn, a cannabinoid synthesis manufacturing system to create rare cannabinoids in the lab that are bioidentical to the compounds derived from the cannabis plant. IntegraSyn uses multiple standard pharmaceutical processes and has achieved a cannabinoid yield of 5 grams per liter, surpassing commercial viability and significantly exceeding currently reported industry yields. InMed is now focusing on manufacturing scale-up to larger batch sizes while continuing process optimization, targeting increased cannabinoid yield and further reducing overall cost of goods.

BayMedica Inc. Acquisition

On June 29, 2021, InMed announced it had entered into a non-binding letter of intent to acquire BayMedica Inc., a private company based in Nevada and California that specializes in the manufacture and commercialization of rare cannabinoids.

As noted in the news release, BayMedica is a revenue-stage biotechnology company leveraging its significant expertise in synthetic biology and pharmaceutical chemistry to develop efficient, scalable and proprietary manufacturing approaches to produce high quality, regulatory-compliant rare cannabinoids for consumer applications. BayMedica is currently commercializing the rare cannabinoid CBC (cannabichromene) as a B2B supplier to distributors and manufacturers marketing products in the health and wellness sector. BayMedica is planning additional rare cannabinoid launches for the coming year.

Pursuant to the indicative terms of the LOI, InMed and BayMedica intend to negotiate and enter into a definitive agreement under which InMed would acquire 100% of BayMedica in exchange for 1.6 million InMed common shares to be issued to BayMedica’s equity and convertible debt holders, with any such issued InMed common shares being subject to a six-month contractual hold period.

Market Outlook

There is a rapidly growing demand for rare cannabinoids. However, their low natural concentration makes traditional harvesting of these compounds cost prohibitive. Biosynthesis allows production of rare cannabinoids in the lab that are bioidentical to compounds found in nature, with significantly higher yields which reduce costs. Biosynthesis can produce pharmaceutical-grade, bioidentical, THC-free compounds at a cost that’s 70 to 90 percent less than wholesale prices of naturally harvested rare cannabinoids.

Cannabinoid-based pharmaceuticals are expected to overtake the market as rare cannabinoids become less expensive and more available. According to Statista, the value of the consumer market for cannabinoid-based pharmaceuticals in the United States is forecast to grow to $25 billion by 2025 and to $50 billion by 2029, with cannabinoid-based pharmaceuticals used to treat health conditions including pain, respiratory conditions, autoimmune conditions and more.

Management Team

Eric A. Adams has been CEO and president of InMed since June 2016. He has more than 25 years of experience in establishing corporate entities, capital formation, global market development, mergers and acquisitions, licensing and corporate governance. He previously served as CEO at enGene Inc. Prior to enGene, he held senior positions in global market development with QLT Inc. (Vancouver), Advanced Tissue Sciences Inc. (La Jolla, CA), Abbott Laboratories (Chicago, IL) and Fresenius AG (Germany).

Bruce S. Colwill is InMed’s CFO. He has more than 25 years of financial leadership experience in public and private companies. Prior to InMed, he served as CFO of General Fusion Inc., a private clean energy company. He was also CFO at Entrée Resources Inc., a mineral exploration company, from 2011 to 2016. He has held CFO roles at Neuromed Pharmaceuticals Ltd., Response Biomedical Corp, Forbes Medi-Tech Inc. and Euronet Worldwide Inc.

Alexandra D.J. Mancini is Senior Vice President, Clinical and Regulatory Affairs at InMed. She has more than 30 years of global biopharmaceutical research and development experience. She has been an executive with numerous biotech companies, including senior vice president of Clinical and Regulatory Affairs at Sirius Genomics; senior vice president of Clinical and Regulatory Affairs at INEX Pharmaceuticals; and vice president of Regulatory Affairs at QLT Inc.

Eric C. Hsu is Senior Vice President, Pre-Clinical Research and Development at InMed. He joined InMed with more than 18 years of scientific leadership experience in the field of gene therapy. He has held various positions within enGene Inc., including vice president of Research and vice president of Scientific Affairs and Operations. He received his Doctorate from the Department of Medical Biophysics at the University of Toronto.

Michael Woudenberg is Vice President, Chemistry, Manufacturing and Controls at InMed. He has more than 20 years of successful drug development, process engineering, GMP manufacturing and leadership experience. He has held positions with 3M, Cardiome Pharma, Arbutus Biopharma and, most recently, was Managing Director of Phyton Biotech LLC.

InMed Pharmaceuticals Inc. (INM), closed Friday's trading session at $0.5703, off by 15.9346%, on 676,547 volume. The average volume for the last 3 months is and the stock's 52-week low/high is $0.4502/$4.75.

Recent News

PaxMedica Inc. (NASDAQ: PXMD)

The QualityStocks Daily Newsletter would like to spotlight PaxMedica Inc. (NASDAQ: PXMD).

PaxMedica Chairman and CEO Howard Weisman participated in a recent Bell2Bell Podcast interview and was joined by Buzz Woods from Corporate Communications

Weisman discussed the company's strategy to seek FDA approval for Suramin as a treatment for Human African Trypanosomiasis ("HAT") and plans for 2024

If PaxMedica is successful in getting approval in HAT, the company believes that could lead to the receipt of a Priority Review Voucher ("PRV")

The company hopes to monetize the PRV to raise funds that will support research and future trials investigating Suramin as a treatment for Autism Spectrum Disorder

PaxMedica hopes to file an investigational new drug application to use Suramin in a large-scale trial in the U.S. in 2024

PaxMedica (NASDAQ: PXMD), a clinical-stage biopharmaceutical company, announced that its groundbreaking research will be published in the "Annals of General Psychiatry," an internationally recognized scientific psychiatry publication. The research was reported in a manuscript titled "Randomized clinical trial of low-dose suramin intravenous infusions for treatment of autism spectrum disorder," which will be published by the psychiatry publication. Written by PaxMedica chief medical officer Dr. David Hough, MD, along with nine coauthors, the article reports on the potential of monthly suramin intravenous infusions as a safe and potentially efficacious treatment for the core symptoms of autism spectrum disorder ("ASD"). Coauthors of the article include Alice Mao, MD; Michael Aman, PhD; Reymundo Lozano, MD, MS; Constance Smith-Hicks, MD, PhD; Veronica Martinez-Cerdeno, PhD; Michael Derby; Zachary Rome; Miel Malan, MD; and Robert Findling, MD. An open access journal emphasizing a biopsychosocial approach to illness and health, the "Annals of General Psychiatry" supports the principles of evidence-based medicine, further validating the significance of this research. "The acceptance of this manuscript represents a significant milestone in PaxMedica's continued dedication to pioneering innovative treatments for autism spectrum disorder," said PaxMedia chief medical officer Dr. David Hough in the press release. "We are honored to contribute to the field of psychiatry with this significant research, underscoring our commitment to advancing the understanding and treatment of ASD."

To view the full press release, visit https://ibn.fm/9Ej95

PaxMedica Inc. (NASDAQ: PXMD) is a clinical stage biopharmaceutical company focusing on the development of novel anti-purinergic therapies (APTs) for the treatment of Autism Spectrum Disorder (ASD) and other serious conditions with intractable neurologic symptoms.

The company’s lead programs are focused on ASD, for which there are currently no approved pharmacologic treatments that target its cause and symptoms. Currently used treatments only address the symptoms of the condition, rather than targeting the pathophysiology itself.

PaxMedica is on a promising path to address these unmet medical needs, bringing hope to millions. Anti-purinergic therapies target the excess production of purines in cells. An overexpression of purines can offset homeostasis and result in an overproduction of cellular adenosine triphosphate, the main energy molecule in all living cells.

The company is headquartered in Tarrytown, New York.

Product Pipeline

PaxMedica is building a robust pipeline of products targeting ASD and related neurodevelopmental conditions. The company’s lead product in development may help eliminate, reduce or modulate some of the more troublesome aspects of ASD. That would open the potential for people with autism to integrate their behavior with others more successfully and improve their lives.

PaxMedica’s lead programs, PAX-101 and PAX-102, utilize the company’s proprietary source of suramin sodium, a broadly acting anti-purinergic therapy that has been known for over 100 years. Its current pipeline includes:

  • PAX-101 (IV Suramin) for ASD – PAX-101 completed a Phase 2B study for ASD in 2021. Suramin is a broadly acting APT and has reported positive results from a dose range study. The results of PaxMedica’s Phase 2B study, which targeted 52 subjects across six sites in South Africa, were presented to AACAP in October 2021.
  • PAX-102 (Intranasal Suramin) – PaxMedica has developed a proprietary intranasal formulation of suramin that is currently being evaluated in ASD and other neurodevelopmental conditions.
  • PAX-101 for HAT – Given suramin’s historical use as a treatment for Human African Trypanosomiasis (HAT), or African Sleeping Sickness, the company is also developing PAX-101 as a treatment for HAT. PaxMedica’s most advanced program is the pursuit of PAX-101 for early-stage East African HAT.
  • Selective APTs – PaxMedica has conducted several preclinical studies to evaluate other APTs that are more selective to specific purinergic receptors and may offer additional benefits over suramin.

Market Opportunity

According to a report by Fortune Business Insights, a leading global market research company, the global ASD therapeutics market was estimated at $1.93 billion in 2022 and is projected to grow from $2.01 billion in 2023 to $3.42 billion by 2030, a CAGR of 7.9% over the forecast period. As there is no current treatment for the core symptoms of autism, PaxMedica believes the addressable market for PAX-101, if approved, could greatly exceed these forecasts.

Autistic disorder, Asperger’s Syndrome and Pervasive Development Disorder are the three main types of ASD, affecting millions of people globally. A 2020 report by the U.S. Centers for Disease Control & Prevention estimated that one in 36 children in the U.S. have been diagnosed with autism disorder.

Several factors are expected to contribute to market growth prospects. A growing prevalence of the condition globally and rising awareness coupled with available treatment options are key factors expected to drive ASD therapeutics market growth during the forecast period. Growing investment in R&D to find effective treatments is also expected to fuel global market growth.

Management Team

Howard Weisman is Chairman and CEO of PaxMedica. He has been a founder and CEO of several specialty pharma and medical device companies. Most recently, he was executive chairman and co-founder of Sofregen, a biotech company. He also served as CEO and president of Seventh Sense Biosystems, a medical device development company. He also was founder, chairman and CEO of EKR Therapeutics, a specialty pharmaceutical company, and founder and COO of ESP Pharma, a company focused on cardio and neurovascular products. He has a bachelor’s degree in chemistry from Rutgers University.

David Hough, M.D., is Chief Medical Officer at PaxMedica. He is a neuroscience clinical development consultant who previously served as vice president at Janssen Research and Development and in various leadership roles over 17 years. Most recently, he was the compound development team leader for SPRAVATO® for treatment-resistant depression. Prior to that, he was the schizophrenia disease area leader. He played a pivotal role in the development programs for oral INVEGA®, INVEGA SUSTENNA® and XEPLION® for schizophrenia. He is a graduate of West Point and is board certified in psychiatry.

Stephen Sheldon is COO and CFO at PaxMedica. He has served as CEO of Thailand-based specialty healthcare company Indochina Healthcare Co. Ltd. since 2015. Previously, he was a consultant for PricewaterhouseCoopers Healthcare Advisory in the Chicago office. He was responsible for developing specialty pharmacy patient programs, strategy development for specialty products and compliance programs. He has an MBA from Thunderbird School of Global Management and a bachelor’s degree in computer science and visual arts from Bowdoin College.

PaxMedica Inc. (NASDAQ: PXMD), closed Friday's trading session at $0.199, off by 9.1324%, on 3,914,247 volume. The average volume for the last 3 months is and the stock's 52-week low/high is $0.1647/$4.07.

Recent News

Appia Rare Earths & Uranium Corp. (CSE: API) (OTCQX: APAAF)

The QualityStocks Daily Newsletter would like to spotlight Appia Rare Earths & Uranium Corp. (CSE: API) (OTCQX: APAAF).

Appia (CSE: API) (OTCQX: APAAF) (FSE: A0I0) today announced that it has completed a high-definition lidar and orthophoto survey across an area of 1,702.50 hectares, which includes the company's priority Ionic Clay Target IV project area in Goias, Brazil. Metro Cúbico Engenharia LTDA, which is headquartered in São Paulo and made up of a multidisciplinary team of professionals with more than 20 years of experience in various technological areas, was engaged by Appia to complete the survey. "Orthophotos are essential for the efficient management of our drill campaign as they provide high-resolution and accurate visual information with maximum detail," said Fabricio Santos, Appia's geophysics and processes manager. "Furthermore, LiDAR surveying provides a highly accurate contribution to terrain modeling, which is essential to ensure the accuracy of the geological model."

To view the full press release, visit https://ibn.fm/SYeQm

Appia Rare Earths & Uranium Corp. (CSE: API) (OTCQX: APAAF) is a mineral exploration company focused on exploration activities at its newly acquired Cachoeirinha rare earths project (“PCH Project”) in Brazil, as well as delineating high-grade critical rare earth elements (REE) and gallium at its Alces Lake property in Saskatchewan. Other properties in Appia’s portfolio include its Elliot Lake Property in Ontario’s historic mining camp, with a large NI 43-101 uranium and rare earths resource. Fully funded with over $5 million (CDN) in cash, no debt, aggressive exploration currently underway, and experienced management, Appia is progressing rapidly on multiple fronts in highly desired market sectors.

The company is headquartered in Toronto, Canada.

Projects

PCH Project-Brazil

The PCH project hosts REE mineralization in both ionic clays developed from the weathering of alkaline granites and in-situ rare earth mineralization associated with the underlying granite and a carbonatite intrusion to depths greater than 100 meters. Sampling data shows enrichment in rare earth minerals to depths of between eight meters and +30 meters.

In early 2023, Appia announced a definitive agreement to acquire a 70% interest in the PCH Project, which is 17,551 hectares in size and located in the Tocantins Structural Province of the Brasília Fold Belt, Goiás State, Brazil. It is classified as an alkaline intrusive rock occurrence with the potential for highly anomalous REE and Niobium mineralization.

The region around Iporá, a city located roughly 30 km from the PCH Project, has significant mineral exploration and mining activity and well-developed infrastructure.

In July 2023, Appia commenced an aggressive auger and reverse circulation (RC) drill campaign to delineate a potential resource estimate at the PCH project. Initial results at the site revealed significant exploration potential with impressive values that often surpass known ionic clay deposits in Brazil, particularly for the highly valuable heavy rare earths Terbium and Dysprosium.

The auger holes drilled at Target 4 have exhibited a range of total REE grades, ranging from 274 ppm to 16,648 ppm (1.66%), with an average of 1,291 ppm total REE. The valuable rare earths used in magnet applications – praseodymium, neodymium, terbium and dysprosium (Pr, Nd, Tb, and Dy) plus yttrium (Y) accounted for approximately 14% of total rare earths, reaching a maximum of 28.4%. Notably, the deposit also contains anomalous values of niobium and scandium, with average values of 736 ppm for Nb and 62 ppm for scandium in a composite sample from Target 4.

Heavy rare earths (HREEs) show maximum values of 1,624 ppm and average values of 1,291 ppm, primarily as terbium and dysprosium. Light rare earths (LREEs) show maximum values of 14,024 ppm (1.54%) with an average of 1,145 ppm. Neodymium and praseodymium, the main magnetic light rare earths, show respective maximum values of 3,131 ppm (Nd) and 885 ppm (Pr) and average values of 216 ppm (Nd) and 61.7 ppm (Pr). The overall HRRE/LREE ratio has a maximum of 39.5% and an average value of 16.67%.

“Appia is thrilled with the progress made and the promising results thus far,” CEO Tom Drivas stated in a news release. “The company remains committed to advancing its exploration plans, aiming to promptly gather significant data throughout the year, and to work towards estimating a maiden mineral resource in the coming months.”

Alces Lake Project – Saskatchewan

Appia’s Alces Lake project, located in northern Saskatchewan, encompasses some of the highest-grade total and critical REEs and gallium mineralization in the world, hosted within several surface and near-surface monazite occurrences that remain open at depth and along strike.

Following the company’s acquisition of additional new mineral claims in the area in February 2023, Appia’s Alces Lake claim block now totals 38,522 contiguous hectares (95,191 acres) – 100% owned by the Company.

Appia announced the completion of a NI43-101 technical report on the property in June 2023, providing an update on exploration previously reported in March 2021.The report is available on SEDAR under the company’s profile.

Extensive diamond drilling and geophysics surveys are underway to explore a more than 25-kilometer structural corridor. In July 2023, the company issued an update on its diamond drill program having completed the first phase of drilling at the project’s Magnet Ridge Zone to further test the extent of the mineralization to the south south-east (SSE). President Stephen Burega noted the presence of “continued mineralization at significantly thicker intercepts.”

As part of its 2023 exploration program at Alces Lake, Appia plans to target priority areas that extend SSE from the Wilson, Richard, Charles, Bell, Ivan, Dylan, Dante and AMP zones through the Magnet Ridge Zone and beyond, covering an area extending approximately 20 kilometers in length and 5 to 7 km in width. Appia will also undertake reconnaissance drilling on priority regional geological and geophysical targets in the Western Anomaly area.

Other Projects

  • Appia holds a total of 75,314 hectares (186,106 acres) of land on four uranium claim blocks in the prolific Athabasca Basin (Loranger, North Wollaston, Eastside and Otherside). Exploration plans for these properties are expected to be announced once permits are in hand.
  • Appia also has a 100% interest in 12,545 hectares (31,000 acres), with rare earth element and uranium deposits over five mineralized zones, in the Elliot Lake Camp, Ontario.

Market Opportunity

A report from Mordor Intelligence forecasts the global REE market is expected to grow from 168 million tons in 2023 to 206.25 million tons by 2028, marking a CAGR of 4.19% during the forecast period. The market is gradually improving following the economic and production restrictions of the COVID-19 pandemic.

Factors driving the market’s growth include high demand from emerging economies and the dependency of environmentally friendly technologies on rare earth elements.

According to UxC, one of the nuclear industry’s leading market research and analysis companies, the uranium market is rapidly becoming production-driven, where spot and long-term prices more closely correlate to the marginal cost of uranium production.

Although global reactor requirements are projected to be flat through 2024, UxC forecasts that significant demand growth from 2025 to 2040 will necessitate new production as resources are exhausted at several uranium projects. In addition, a large percentage of production exists in regions of the world with high geopolitical risk, which makes the market vulnerable to future disruptions and price volatility.

Management Team

Tom Drivas is CEO of Appia Rare Earths & Uranium Corp. He is an entrepreneur with over 30 years of experience in various industries, including over 20 years in the mineral resource industry. He is also currently a director of Romios Gold Resources Inc., a publicly traded company he founded in 1995.

Stephen Burega is President of Appia. He brings 16 years of management and operations experience in the mining and natural resources sectors. His extensive emerging markets background, along with a deep understanding of stakeholder management, social development and structured community engagement, position him well to lead Appia’s First Nations community engagements. He is also President and CEO of Romios Gold Resources which is focused on base and precious metal exploration in North America.

Frank van de Water is the company’s CFO. He holds CPA and CA designations and has been involved with international mining, metals and resource companies in North America, Latin America, Europe and Africa for more than 40 years.

Dr. Irvine R. Annesley, Ph.D., is VP Exploration at Appia. He is a licensed geoscientist (P.GEO.) and Professor in Economic (Mining and Mineral Exploration) Geology at École Nationale Supérieure de Géologie in France and an Adjunct Professor in Geology at the University of Saskatchewan. He has over 35 years of global exploration and applied research experience in uranium, gold and base metals exploration, most recently with Athabasca uranium explorer JNR Resources Inc.

Don Hains, P.Geo., is the company’s Consulting Geologist and Qualified Person Consulting Industrial Minerals Expert.

Antonio Vitor is Appia’s Country Manager, Brazil. He has a track record as a portfolio manager and board member. He has held multiple significant positions, including Territory Manager at Shell, as well as Senior Project Planning and Consulting roles at PwC and Petrobras.

Jack Lifton is the company’s Senior Technical Advisor and Consultant. He is an author and lecturer on the market fundamentals of technology metals.

Appia Rare Earths & Uranium Corp. (OTCQX: APAAF), closed Friday's trading session at $0.1596, off by 5.3268%, on 343,240 volume. The average volume for the last 3 months is and the stock's 52-week low/high is $0.075/$0.35685.

Recent News

Sharing Services Global Corporation (SHRG)

The QualityStocks Daily Newsletter would like to spotlight Sharing Services Global Corporation (SHRG).

Sharing Services Global Corporation (SHRG), formerly Sharing Services Inc., is a diversified company dedicated to maximizing shareholder value, operating through two primary subsidiaries: Elepreneurs Holdings, a direct-selling company, and Elevacity Holdings, a products company. Headquartered in Plano, Texas, SHRG markets and distributes Elevate-branded health and wellness products through an independent sales force of distributors called Elepreneurs.

Proprietary Products

SHRG’s current exclusive Elevate product offerings are marketed under the Elevacity brand, so named to signify the company’s commitment to elevating lives.

The Elevate health and wellness product line consists of nutraceutical products that SHRG refers to as D.O.S.E., which stands for dopamine, oxytocin, serotonin and endorphins – all of which are key hormones proven to promote happiness and well-being.

Elevacity brand products are carefully formulated, chosen and designed to support a single objective: elevate the happiness and well-being of the consumer.

Global Network of Elepreneurs

Elevacity products are shared and sold by a growing international network of home-based entrepreneurs, called Elepreneurs, operated by Elepreneurs Holdings. This SHRG subsidiary provides basic and advanced programs for both new and experienced entrepreneurs who are focusing on their direct-sales careers.

SHRG’s high-performing independent sales force follows the company’s Blue Ocean selling strategy, an approach that encourages individuals to seek new markets, lead, and to “stop competing and start creating.” The Blue Ocean strategy is based on the book, “Blue Ocean Strategy,” written by Professor Renée Mauborgne, who notes that “the lesson here is that the best defense is offense, and the best offense… is to make a blue ocean shift and create your own blue ocean.”

Following this selling strategy, SHRG’s Elepreneurs are taught that, rather than competing directly in a competitive, direct-selling market, they should focus on making competitors irrelevant and succeeding in an uncontested marketplace.

In addition, SHRG’s Elepreneurs use the interactive, video-based VERB sales-marketing platform developed by Verb Technology Company Inc. The app utilizes proprietary interactive video data collection and analysis technology and provides next-generation customer relationship management, lead generation, and video marketing software applications.

Continued Momentum as Industry Leader

These selling strategies have resulted in sharp and consistent revenue gains. In the company’s 10-Q filed with the SEC for the three months ended Oct. 31, 2019, SHRG reported sales of $38.8 million for fiscal Q2 2019, an increase of 116% over sales of $17.9 million reported for the comparable quarter of 2018. Consolidated gross profit jumped by $16.2 million to $27.4 million for the same period compared to Q2 2018.

SHRG’s consolidated operating earnings were $3.9 million in the fiscal quarter ended Oct. 31, 2019, compared to $866,802 for the comparable period the prior year. Consolidated gross margin also grew 70.9% for the three months ended Oct. 31, 2019, compared to 62.2% the prior year.

These numbers are continuing a trend established over the past two years. In fiscal Q1 2019, SHRG achieved revenues of $35.4 million, more than double that of the comparable period in 2018. Even earlier, the company reported sales of $85.9 million for fiscal year ended April 30, 2019. This represents a nine-fold increase, or $77.5 million jump, over the company’s revenues of $8.4 million the prior year.

These numbers bring SHRG’s sales revenues since December 2017 — when the company’s Elevate product line was released — to an impressive cumulative total of $169 million.

Preparing for Success

SHRG is well prepared to continue and accommodate for this growth. The company recently expanded its corporate footprint by moving to a 10,000-square-foot facility in Plano, Texas, that offers ample room to expand as the company grows and flourish. The larger corporate locale provides space for a growing customer service department, product fulfillment, opportunity and training rooms, as well as a video production suite.

In addition, the company has a seasoned, expert leadership team in place, led by John “JT” Thatch. Thatch was appointed president and CEO of SHRG in March 2018, bringing to the company his expertise obtained from successfully starting, owning and operating several businesses in various industries. His experience with corporate growth, acquisitions, financing and negotiation in fast-paced and flexible environments will significantly assist SHRG as the company aims to expand and increase revenues.

Contact
469.304.9400 x 201
Info@SHRGinc.com
http://www.SHRGinc.com

Sharing Services Global Corporation (SHRG), closed the day's trading session at $1.01, up 23.17%, on 276,351 volume with 217 trades. The average volume for the last 3 months is 279,074 and the stock's 52-week low/high is $0.27/$2.54.

Recent News

Starco Brands Inc. (OTCQB: STCB)

The QualityStocks Daily Newsletter would like to spotlight Starco Brands Inc. (OTCQB: STCB).

Starco Brands Inc. (OTCQB: STCB) is a modern-day invention factory. The company’s unwavering mission is to invent and acquire consumer products and brands with behavior-changing technologies that spark excitement in the everyday.

This consumer product company has grown from a few million dollars in revenue to a current run rate of approximately $67 million in annual revenue in one year.

The company has succeeded by identifying whitespaces in eight core consumer categories and then either: 1) leveraging its internal R&D capabilities and dedicated manufacturing network to invent new technologies and brands or 2) utilizing the management team’s extensive M&A experience to acquire brands that fill the industry void, delighting consumers and retailers alike.

Whether the brand is developed internally or acquired, the company employs a modern marketing playbook to ensure its brands are at the forefront of culture; garnering unprecedented media attention and engagement that supports a robust sales network.

Starco Brands’ core competencies are inventing technologies, acquiring companies, marketing, building trends, pushing awareness, penetrating media (social and otherwise) and executing cutting edge pull-through strategies with a roster of globally recognized celebrities, influencers and media and distribution partners.

A commitment to changing the way people approach everyday activities is innate in the company’s corporate DNA.

The company is based in Santa Monica, California.

Brands

Whereas other consumer products companies are content with evolution, Starco Brands has its mind set on creating a revolution across the industry. From disrupting the spirits industry with Whipshots, the world’s only vodka-infused whipped cream, to Soylent, the original food tech company, Starco Brands is putting the CPG world on notice. Its portfolio of brands includes:

  • Whipshots is a first-of-its-kind alcoholic whipped cream launched in 2021 with celebrity partner Cardi B. Consumers have embraced this boozy concoction, putting it on top of cocktails, coffees and desserts, or enjoying it straight from the can. In just over a year, the brand has sold over 2 MILLION cans, making it one of the fastest growing spirits in history.
  • Winona Pure gives consumers movie theatre popcorn in the comfort of their own homes. All the flavor and none of the additives is the story behind these all-natural, non-GMO popcorn seasoning sprays. A simple spray is all it takes to add the perfect pop of flavor to the classic theatre treat.
  • Art of Sport, co-founded by the great Kobe Bryant, is the number one body care brand for athletes. With a growing line of personal care products tested by the world’s greatest athletes, these daily skin essentials give consumers everything they need to feel fresh, stay protected and confident and perform at their peak every day.
  • Skylar is the first and only line of perfumes on the market that are hypoallergenic and safe for sensitive skin. With the strong support of industry titan Sephora, the brand has quickly attracted a loyal following.
  • Soylent is a technological feat. Originally funded by Google Ventures and Andreessen Horwitz, Soylent is dubbed as the world’s most perfect food. Made from sustainably grown plant-based ingredients, Soylent’s line of products is scientifically developed to provide all the functional ingredients, vitamins, minerals, fats, carbohydrates and protein that the body needs – all in convenient, delicious and affordable packages. Soylent’s innovative product line-up includes complete nutrition powders, ready-to-drink shakes, 100-calorie snack bars, high protein nutrition shakes and energy boosting nutrition shakes. Soylent was also the recipient of the 2023 Product of the Year Award by Kantar, a global leader in consumer research.

With award-winning marketing talent, Starco Brands develops robust, integrated marketing plans for every brand in its portfolio, ensuring an impactful presence across all verticals.

Market Outlook

Starco Brands’ varied brand portfolio gives it access to the growth of numerous product categories that are ripe for innovation.

Through its February 2023 acquisition of complete nutrition pioneer Soylent, Starco Brands is positioned to capitalize on the projected growth of the plant-based nutrition space. Research firm Statista valued the plant-based nutrition market at $29.4 billion in 2020 and forecasts its value at nearly $162 billion by 2030, representing a CAGR of 18.7% for the period.

Likewise, Starco Brands gained improved access to the global fragrance market through its December 2022 acquisition of Skylar. According to a report by Grand View Research, the global perfume market was valued at $50.85 billion in 2022 and is expected to grow to a value of nearly $80 billion by 2030, achieving a CAGR of 5.9% over the forecast period.

The company is primed to expand its access to other growth verticals as it advances on its path to invent and acquire behavior-changing technologies and brands.

Management Team

Ross Sklar is the CEO of Starco Brands. A chemical formulator by trade, he started his first company while still in college. Since 2004, he has made over a dozen acquisitions with multiple exits and controls an eclectic collection of industrial, household, personal care and food and beverage manufacturers covering many consumer-packaged goods categories.

Darin Brown is the Chief Operating Officer of Starco Brands. With over 20 years of experience in chemical manufacturing, business development, finance and mergers and acquisitions, he has scaled the company from the ground up. He oversees all internal operations for Starco Brands and is an integral liaison between the company and Mr. Sklar’s manufacturing facilities.

David Dreyer is Chief Marketing Officer of Starco Brands. With over 25 years of experience working with blue chip and startup brands, he oversees all marketing initiatives for the company. Mr. Dreyer comes to Starco having worked with such standout brands as Apple, Pepsi, Pizza Hut, Dr Pepper, Snapple, Infiniti, The GRAMMY’s, Honda and Stamps.com. He is also a Professor of Advertising at USC’s Annenberg School for Communication.

Starco Brands Inc. (STCB), closed Friday's trading session at $0.14, even for the day. The average volume for the last 3 months is and the stock's 52-week low/high is $0.115/$0.265.

Recent News

HeartBeam Inc. (NASDAQ: BEAT)

The QualityStocks Daily Newsletter would like to spotlight HeartBeam Inc. (NASDAQ: BEAT) .

HeartBeam Inc. (NASDAQ: BEAT) is a cardiac technology company that has developed the first and only 3D-vector 12-lead electrocardiogram (ECG) platform for heart attack detection anytime, anywhere. The company’s proprietary ECG telehealth technology aims to redefine the way high risk cardiovascular patients are diagnosed in ambulatory and acute care settings. HeartBeam’s initial focus is on providing diagnostic data to help physicians with care management of patients with cardiovascular disease.

In August 2022, HeartBeam announced that it submitted its HeartBeam AIMI™ software for approval from the U.S. Food and Drug Administration (FDA). HeartBeam AIMI is a platform technology to improve the speed and accuracy of heart attack detection in acute care settings. The company expects FDA approval by the end of 2022, and a full commercial roll-out of HeartBeam AIMI is targeted for Q1 2023.

HeartBeam sees submission of its first product based on its platform technology as an important milestone toward commercialization, which underscores the company’s continued progress toward making the HeartBeam AIMI platform widely available to help emergency department physicians quickly and accurately identify a heart attack.

While the FDA conducts its regulatory review, HeartBeam will focus on executing key components of its commercialization plan and subscription revenue model. It will also continue to engage in discussions with strategic institutions, including academic centers, regional healthcare systems and regional community hospital systems that can utilize HeartBeam products.

The company is based in Santa Clara, California.

Products

HeartBeam’s development portfolio includes two products:

  • HeartBeam AIMI is software that provides a 3D comparison of baseline and symptomatic 12-lead ECG to more accurately identify a heart attack in acute care settings and, as noted above, has been submitted for FDA approval; and
  • HeartBeam AIMIGo™, the first and only credit card-sized 12-lead output ECG device coupled with a smartphone app and cloud-based diagnostic software system for remote heart attack detection.

HeartBeam is developing AIMIGo, a medical-grade detection and monitoring technology for use in remote heart attack detection, thereby allowing physicians to diagnose a patient’s heart attack as it occurs, even if the patient is not at a medical facility. The company’s system, once approved by the FDA, can be used by patients at home or almost anywhere and anytime to help their physicians assess whether chest pain is the result of a heart attack or another cause. While approximately 82% of chest pain ED visits are unnecessary, patients delay approximately 3 to 4 hours after symptoms begin, increasing mortality rates by 40%. The company’s goal is to shorten the time to treatment outside of the medical facility to improve patients’ well-being.

HeartBeam’s AIMIGo is a powerful, portable and easy-to-use prescription-based product. It comprises a smartphone app, a credit card-sized ECG device placed on a patient’s chest, the HeartBeam cloud platform, and a digital portal for the physician to view ECG results and direct patient action. For the first time outside of a medical setting, HeartBeam AIMIGo enables patients and their clinicians to determine if symptoms are due to a heart attack, quickly and easily, so care can be expedited, if needed.

Pending FDA clearance, AIMIGo is initially intended to be available by prescription, and is reimbursable under existing remote patient monitoring codes (RPM codes). This provides a new revenue stream to physicians who before did not have a way to monitor these high-risk patients. The RPM codes provide a monthly reoccurring revenue stream to the company, as well. On average, at current reimbursement rates, the practice will receive $1,300+ per year per patient they monitor, and the company will receive $600 per year per patient from this RPM reimbursement.

Market Overview

Adoption rates of telehealth services increased dramatically in recent years, with the COVID-19 pandemic serving as a major driver of growth. Among the areas seeing the greatest expansion are cardiology, radiology, behavioral health and online consultation.

Encouraging this growth, governments are actively developing new policies and reimbursement guidelines to promote the use of digital health platforms. The U.S. Centers for Medicare & Medicaid Services (CMS), for example, has recently expanded reimbursement for telehealth services. U.S. market growth is also being driven by the rising prevalence of chronic conditions and the growing geriatric population.

Remote heart attack detection is a previously unsolved problem with a massive and underserved market that is several times larger than the $2 billion total addressable market (TAM) in the U.S. for ECG cardiac arrhythmia monitoring.

Approximately 8 million Americans have suffered at least one heart attack, and a total of 18 million have been diagnosed with coronary artery disease (CAD). Based on these figures, HeartBeam projects a total addressable U.S. market TAM valued at $10 billion annually for its AIMIGo solution for remote heart attack monitoring of CAD.

Management Team

Branislav Vajdic, Ph.D., Chief Executive Officer and Founder of HeartBeam, Inc, combines over 30 years of experience in technology development and senior management positions. Dr. Vajdic has been deeply involved with the development of HeartBeam’s technology to fit his vision for the company. Prior to HeartBeam, from 2007 to 2010, Dr. Vajdic was CEO and Founder of NewCardio, a publicly traded company in the cardiovascular devices space. From 1984 to 2007, Dr. Vajdic was at Intel, where he held various senior management position. At Intel, Dr. Vajdic was the designer of first Flash memory and two key inventions that enabled Flash as a product and led engineering groups responsible for Pentium 1 through Pentium 4 designs. Dr. Vajdic was awarded two Intel Achievement Awards, the highest level of award for outstanding contributions to Intel. Dr. Vajdic is author of numerous patents and publications in the fields of cardiovascular devices, as well as chip design. Dr. Vajdic holds a Ph.D. in Electrical Engineering from the University of Minnesota.

Jon Hunt, Ph.D., has over 35 years’ experience in the medical/medical device industry with extensive domestic and international experience in general management, clinical/regulatory, sales and marketing. He also has diverse experience in Fortune 500 companies, as well as start-up environments. Dr. Hunt was the Vice President of Clinical Science and Technology, Medical Device Innovation Consortium, from July 2019 to July 2021, and Vice President of Clinical and Regulatory Affairs, Cryterion Medical from January 2018 to June 2019 (acquired by Boston Scientific Corporation in July 2018 for $202M). Dr. Hunt was the Founding President and CEO of Bardy Diagnostics, Inc. from October 2013 to November 2017 (acquired by Hill-Rom Holdings, Inc.). Prior to joining Bardy Diagnostics, Dr. Hunt spent the previous 11 years as the Vice President of Clinical & Regulatory Affairs with Cameron Health, Inc. (acquired by Boston Scientific Corporation). Dr. Hunt spent the previous 10 years with Cardiac Pacemakers, Inc., St. Jude Medical and Cardiac Pathways Corporation. Dr. Hunt began his career with Cardiac Pacemakers, Inc. (now Boston Scientific Corporation) as the Director of Clinical Programs. He subsequently held positions at St. Jude Medical in Clinical Affairs and as the Business Unit Director for the Cardiac Rhythm Management division for Europe, the Middle East and Africa. At Cardiac Pathways Corporation, Dr. Hunt held various executive positions as Vice President of International Sales and Marketing and Vice President of Worldwide Sales and Marketing (acquired by Boston Scientific Corporation). Dr. Hunt received his Ph.D. in Motor Control from The Pennsylvania State University, his Master’s from California State University, Long Beach and his undergraduate degree from Keele University in the United Kingdom.

Rick Brounstein, HeartBeam’s Chief Financial Officer, combines over 30 years of experience in health technology senior management. Since 2017, Mr. Brounstein has been and is currently a partner of Hardesty, LLC, a financial services firm, and Mr. Brounstein is currently a managing director of CTRLCFO, LLC, a firm Mr. Brounstein founded in 2016 to support funded start-ups in life science and technology. From 2008 to 2011, Mr. Brounstein was Chief Financial Officer of NewCardio, Inc., a microcap public company in the cardiology space, and, over his career, he has been with nine other companies in life science or technology, holding positions including Chief Financial Officer, Chief Operating Officer, Treasurer and Accounting Manager. From June 2001 through November 2007, Mr. Brounstein held several positions at Calypte Biomedical Corporation, a publicly traded medical device company, including Chief Financial Officer and Executive Vice President. In January 2007, Mr. Brounstein was appointed as the National Member Representative for the 2007 COSO Monitoring Project, which published new guidelines for monitoring internal financial controls in February 2009; Mr. Brounstein subsequently was a member of the FEI task force that issued the updated COSO Internal Control Framework in 2013. In March 2005, Mr. Brounstein was appointed to the SEC Advisory Committee on Smaller Public Companies. Mr. Brounstein earned his Certified Public Accountant (CPA) certification while working at Arthur Andersen LLP, formerly a public accounting firm. Mr. Brounstein holds a B.A. in accounting and an M.B.A. in finance, both from Michigan State University.

Ken Persen, HeartBeam’s Chief Technology Officer, combines over 28 years of experience in the medical device and digital health industries in engineering and senior management positions. Mr. Persen has been involved in several companies in Cardiac Rhythm Management, holding positions including Chief Executive Officer, Chief Technology Officer, Executive Vice President and Director of Engineering. Since 2016 and prior to joining HeartBeam, Mr. Persen was the Chief Technology Officer at LIVMOR, Inc., a digital health company. In addition, from 2016 through November 2021, he was also Chief Executive Officer of LIVMOR. Prior roles included Director of Engineering at Cameron Health (acquired by Boston Scientific), a late-stage medical device start up, and engineering and management positions at Guidant Corp. (acquired by Boston Scientific), a large medical device manufacturer. He has an undergraduate degree from University of Minnesota, Duluth, with a BA in Computer Science.

HeartBeam Inc. (NASDAQ: BEAT), closed Friday's trading session at $1.29, off by 1.5267%, on 20,358 volume. The average volume for the last 3 months is and the stock's 52-week low/high is $1.25/$6.00.

Recent News

Near Intelligence Inc. (NASDAQ: NIR)

The QualityStocks Daily Newsletter would like to spotlight Near Intelligence Inc. (NASDAQ: NIR).

Near Intelligence Inc. (NASDAQ: NIR), a global Data Intelligence Platform, curates one of the world’s largest sources of intelligence on people and places. Near’s patented technology analyzes data to deliver insights on approximately 1.6 billion unique user IDs across 70 million points of interest in more than 44 countries. With Near’s three-pillared approach – high-quality data, privacy, and AI – operational and marketing leaders are empowered with solutions to successfully engage and grow their businesses at scale. With a presence in Pasadena, San Francisco, Paris, Bangalore, Singapore, Sydney, and Tokyo, Near serves enterprises in diverse industries, including retail, real estate, restaurants, travel/tourism, telecom, media, and more.

Established in 2012, Near employs vast data volumes to comprehend consumer behavior across digital and physical realms, ensuring privacy compliance through anonymization and aggregation. The company analyzes behavior around visited places and connected devices.

Near is headquartered in Pasadena, California.

Platform and Services

The Near platform delivers global, high-quality data in a privacy-safe environment, evaluating consumer activity across physical and digital spaces to provide business leaders with deep insights into the places their customers frequent, along with their brand and competitor preferences.
It is built on three fundamental tenets:

  • Global, High-Quality Data: The Near Platform provides high-quality insights about people and places from diverse industries and applications. Through complex data refinement processes, Near converts raw data into powerful insights that empower decision-makers with actionable information.
  • Privacy and Transparency: Data privacy and transparency are deeply ingrained in Near’s foundation. The platform is built on the principle of privacy by design, ensuring that data privacy considerations are integrated into every aspect of its products, processes, and practices. The Near approach empowers business decision-makers with control over their information and adheres to the most stringent global privacy regulations.
  • Data Science and AI Innovation: The Near Platform employs advanced algorithms and machine learning models to deliver high-quality insights, so users can decipher complex consumer behavior patterns and trends.

In August 2023, Near illustrated the value of its intelligence platform in one such industry – quick-service restaurants (QSRs). Many of the world’s largest QSR brands count Near as a trusted partner for high-quality data insights and restaurant analytics. By harnessing Near’s advanced analytics capabilities, top QSRs with combined annual revenues approaching $90B are able to understand consumer movement and behavior patterns, brand affinities, trade areas, and trends.

The company also collaborates with partners to strengthen their datasets by integrating Near’s physical and digital world understanding. Near’s data is always delivered with a privacy-first, consent-led approach via its SaaS-based geospatial analytics platform.

Market Outlook

An analysis from Fortune Business Insights estimated the global business intelligence market was valued at $27.11 billion in 2022 and is projected to grow from $29.42 billion in 2023 to $54.27 billion by 2030, a CAGR of 9.1% during the forecast period.

According to the report, global market growth can be attributed to the increasing adoption of cloud-based Artificial Intelligence/Machine Learning services and data analytics across organizations. A surge in demand for flexible architectures and adaptable solutions opens up market expansion opportunities.

Management Team

Anil Mathews is the CEO of Near. He is a visionary who has spent the past 22 years as a serial entrepreneur, building successful businesses around engineering, messaging, and social. He is passionate about creating new market companies with a strategic vision and technology capability that can provide substantial growth. He is also an advisor and investor to numerous startups across the globe.

Shobhit Shukla is President of Near. He currently runs the company’s global business and strategic initiatives, where he is responsible for executing Near’s vision to become the most accurate and privacy-safe source of intelligence on people and places. He holds an MBA from the Indian Institute of Management and advises multiple early-stage startups on growth strategy.

Gladys Kong is COO of Near. She was previously CEO of UberMedia, a data intelligence company acquired by Near. She was also CEO of Go Interactive, a fantasy sports company. Before that, she held Engineering and R&D vice president positions at Snap.com and Idea Lab. She has a bachelor’s degree in engineering and applied science from Caltech and a master’s degree in computer science from UCLA.

Rahul Agarwal is the CFO of Near. He began his career at PwC India and later held accounting and finance roles at HT Media and InMobi, where he rose to the position of Head of Finance, North America. He is a graduate of The Institute of Chartered Accountants of India and holds an MBA in finance and strategy from the Indian Institute of Management at Bangalore.

Near Intelligence Inc. (NASDAQ: NIR), closed Friday's trading session at $0.147, off by 8.125%, on 590,039 volume. The average volume for the last 3 months is and the stock's 52-week low/high is $0.142/$18.65.

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Prime Harvest Inc.

The QualityStocks Daily Newsletter would like to spotlight Prime Harvest Inc.

Prime Harvest Inc., based in San Diego, California, is a technology-focused, full-service cannabis company with horizontally diversified operations spanning various segments of the cannabis value chain, from licensing acquisition and compliance management to direct-to-consumer operations. The company is leveraging a long-term strategy of investing in the growth and scale of licensed assets anchored by the power of data-driven technology to expand its footprint throughout California.

Sustainability is key to Prime Harvest’s corporate vision. The company aims to ensure that the communities it serves capture their fair share of the fruits of the industry’s growth, including financial profit, employment opportunities, environmental enrichment and impactful innovation through R&D and education.

The company’s mission is to appeal to the ethos of the cannabis consumer by setting a new operational standard emphasizing accountability, sustainability and community. With this commitment, Prime Harvest continues to work toward positively affecting millions of lives through the creation of a world-class platform that caters to strengthening the commercial cannabis pipeline.

Jaxx Cannabis

Jaxx Cannabis is the flagship brand in Prime Harvest’s portfolio. Through Jaxx Cannabis, the company aims to use technology to facilitate a true customer-centric culture while enhancing the overall craft cannabis experience. Jaxx features an expertly curated selection of premium products from some of the most respected brands in the thriving California market.

Key values serving as the foundation of Jaxx Cannabis include:

  • Creating and nurturing a welcoming culture for all
  • Unlocking the true potential of customer value
  • Being innovative in uncovering new ways to grow both the company and the industry
  • Meeting the wants and needs of consumers to promote profitability
  • Remaining accountable for the results of its operations

It is these values that differentiate Prime Harvest and Jaxx Cannabis in the California cannabis sector.

Brand Partnerships

Prime Harvest works diligently to establish strong alliances with complementary brands that are in alignment with its culture and values. Through a combination of deliberate foresight and strategic action, the company seeks to grow existing cannabis brands and continuously discover new, high-potential performers that are primed for long-term success.

These partnerships enhance Prime Harvest’s efforts to transform the world’s cannabis access and bring its consumers high-quality products that are fair for both people and the planet.

Responsibility

Prime Harvest remains committed to the goal of creating a more sustainable environment, now and in the future. Concern for human beings and the environment can be observed in every facet of its operations, including its ongoing R&D activities dedicated to exploring methods of reducing and repurposing waste into composite materials and exploring the potential of the hemp plant for industrial and wellness contributions.

The company is a proud member of the Community Alliance Program, a foundation that seeks to make a difference in local communities by providing financial assistance for educational programs, housing homeless veterans, creating urban farms, and holding local arts initiatives for children and adults. The program also helps explore the natural healing attributes of medical cannabis through research, development, clinical trials, and advocating for the safe access of cannabis to those in need.

Market Overview

Ongoing changes in U.S. state government policies toward cannabis are expected to cause demand for legal marijuana to surge. In addition, the number of indications for which medical marijuana is prescribed continues to increase. These factors are expected to rapidly boost legal sales of cannabis products.

Legal sales across the U.S. hit a record of $17.5 billion in 2020, marking an increase of 46% over 2019, according to Forbes. This strong growth is expected to continue. According to a Grand View Research report, the global legal marijuana market is forecast to grow at a CAGR of 26.7 percent from 2021 to 2028.

California – Prime Harvest’s home state – has consistently led the pack in terms of U.S. cannabis sales. The Motley Fool pegged cannabis spending in the Golden State at $3.8 billion in 2020, more than doubling the second state on its list.

Leadership Team

The Prime Harvest team is composed of true experts in their respective fields focused on building a world-class organization capable of driving the cannabis industry and movement forward.

E. Duane Alexander is the company’s Founder and CEO. He brings to the team more than 25 years of real-world, hands-on cannabis retail, marketing and commercial operations experience. Mr. Alexander has championed 40+ cannabis license applications throughout the western U.S. to date.

John Wilczak is the COO of Prime Harvest. He has 30+ years of executive management, strategy development & configuration experience with GE, pharmaceutical and agriculture companies. Mr. Wilczak is a Brown & Columbia MBA with vast knowledge of technology driven intellectual properties.

Andrea Jenson is the Chief Financial Officer of Prime Harvest. As CFO, she is responsible for all the company’s financial functions, including accounting, corporate finance and investor relations. Her career spans more than 20 years of varied experience in financial management, business leadership and financial strategy.

John Kazanjian is the VP of Business Development of Prime Harvest. He has worked over 40 years in business operations, brand marketing, sales and investor/lender communications. Mr. Kazanjian earned his B.S. from Rutgers University and his MBA from Harvard University.

Johann Balbuena is the Chief Marketing Officer of Prime Harvest. She has more than six years of experience in California cannabis licensing acquisition and compliance management. Ms. Balbuena has led multimedia production and content marketing efforts for the likes of the Social Club TV app, The Emerald Cup, High Times, Weedmaps and Synergy.


Recent News

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Utopia VR

The QualityStocks Daily Newsletter would like to spotlight Utopia VR

Utopia VR is one of the world’s first ‘Metaverse-As-A-Service’ solutions for business. The company’s hosted and managed subscription software provides businesses a low barrier to entry, browser-based, device agnostic platform where they can manage their own private 3D metaverse meeting spaces. Users can host and attend Zoom-like virtual meetings in lifelike virtual reality – with no software downloads – engaging their audiences in a more collaborative and fun way.

Utopia VR has many technology and privacy advantages over solutions built on other metaverse marketplaces such as Horizon Worlds (META) or Decentraland. Utopia VR works on all devices – PC, mobile and virtual reality headsets – whereas many competitors only work in VR or on PC.

Utopia VR is headquartered in Kelowna, B.C.

Products

Utopia VR’s The Metaverse for Everyone™ is a one-click, web-based, avatar-driven, mobile-friendly audio- and video-conferencing platform that utilizes innovative 3D web technology. Utopia VR’s virtual platform works on digital devices including PCs, mobile phones and VR headsets such as Oculus Quest or HTC Vive. No software or proprietary hardware is needed.

Users navigate through the various VRoom environments by using avatars. Users can walk, talk and sit – just like they do in the real world. A user’s avatar can be controlled with a computer keyboard, smartphone or virtual reality headsets. Text chat, voice and video is ever-present and used to communicate with others in the VRoom. For important meetings and presentations, users can also import audio, video, 2D art and images, animated 3D objects, PDF files and their favorite NFTs by simply dragging and dropping files into a VRoom or pasting a video link from supported media platforms.

Organizations that have an existing website can transition their digital assets, including text, images, video, PDFs, slideshows and more, to VRoom environments with a simple copy and paste. This will allow their customers and audiences to experience their brand in a whole new, immersive environment.
Utopia VR’s mobile app enables users to personalize their own 3D environments and then schedule business meetings or social meetups in seconds through a proprietary link management system. The app is available for iPhone and iPad users. The company’s website mirrors the app, which means users can access Utopia VR directly from a PC, laptop, tablet, or VR headset without downloading the app.

Market Outlook

Regarded as the next iteration of the internet, the metaverse is a virtual space where the physical and digital worlds coexist and interact, encompassing virtual reality, augmented reality, extended reality and mixed reality, as well as making use of artificial intelligence and other technologies.

Data consolidator Statista estimated that the global metaverse market size stood at $38.85 billion in 2021 and projected the market would grow to be worth $47.48 billion in 2022. From there, Statista forecasts the value of the metaverse market will explode to reach $678.8 billion by 2030, achieving a CAGR of more than 39% over the period.

The metaverse could create $5 trillion in opportunity by 2030, according to McKinsey & Company.

Management Team

Stuart Gray, President, Co-Founder and director of Utopia VR, has been an officer and director for both private and publicly traded companies and has led public offerings for junior listed companies that have gone on to realize multibillion-dollar market valuations. He previously was a consultant and quarterbacked taking eXp World Holdings Inc. (NASDAQ: EXPI) public. eXp is a disruptive, no bricks and mortar, real estate brokerage firm with 85,000 agents worldwide using its virtual, software-based, metaverse platform for closing transactions, training and events.

Cory Braden, CTO and director of Utopia VR, is a forward-thinking strategic leader with over 20 years of experience in delivering software as a service. Recognized for a positive leadership style and excellent communication skills, he is well-versed in user experience, complex application architectures, cloud infrastructure and management of high-performance teams.

Terry Woloszyn, VP of Sales and Advisory at Utopia VR, brings vast technical and sales experience to the company. Before joining Utopia VR, he conceived and launched a data security startup and graduated from two startup accelerator programs. He has personally raised $20 million in equity venture funding.

Recent News

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OK Stone Engineering Inc.

The QualityStocks Daily Newsletter would like to spotlight OK Stone Engineering Inc.

OK Stone Engineering Inc. is a Texas-based company formed to manufacture engineered quartz slabs to be used as materials for countertops and tile in the building and construction industry. The company’s manufacturing process uses next-generation technologies which reduce costs, improve the quality of the finished product and increase safety of workers in the manufacturing process.

OK Stone is the first high tech source of U.S.-made quartz stone products. The company, with joint venture partner Breton S.p.A., has announced a new factory for engineered stone in Fort Worth, Texas, to fill the massive supply gap in the U.S. market, where the domestic shortage is projected to increase to 140 million square feet annually by 2026. Construction of the facility is scheduled to begin in 2024, with production projected to start in mid to late 2025 and the is facility projected to be scaling to full production in early 2026.

The factory will be the first in the U.S. to employ Breton’s Bioquartz® technology, a transformative state-of-the-art manufacturing process. There are only nine engineered stone slab manufacturers in the U.S., and seven of those are based on older Breton technology. Only OK Stone is investing in this latest technology while other manufacturing facilities risk falling behind.

Products

OK Stone’s licensed Bioquartz® manufacturing technology, which has been under development for a decade, will provide a significant competitive advantage in the market by solving the most frustrating problems faced by customers. Breton, based in Italy, is the definitive international leader in designing and developing engineered stone production plants, with more than 95% of global market share.

This next-gen manufacturing technology will allow OK Stone to source a more reliable and less expensive supply of domestic raw materials, replacing variable supplies from Asia. It also reduces costs by more than 10% while producing quartz slabs with an unlimited range of aesthetic effects that older manufacturing technologies cannot replicate.

Importantly, the Bioquartz® process eliminates the risk that workers can develop silicosis, an incurable lung disease caused by inhaling crystalline silica particles. Expected new government regulations to prevent silicosis are likely to impact other U.S. manufacturers. The company’s expected regulatory compliance, as well as its avoidance of international shipping costs for raw materials – which have been unstable since 2021 – are among the factors likely to provide OK Stone with major competitive advantages in the market.

The company will sell its factory output through the existing network of stone distributors that supply the building and construction industry.

Market Opportunity

According to a report by Allied Market Research, a research, consulting and advisory firm, the global engineered stone market was valued at $21.1 billion in 2021 and is projected to reach $35.1 billion by 2031, growing at a CAGR of greater than 5% for the forecast period.

Engineered stone is used in a number of applications in the construction industry, including countertops, flooring and wall tiles, fireplaces and more. The report states that rapid expansion in construction is boosting the global demand for engineered stone.

Management Team

OK Stone’s management team recently designed, built and operated a Breton factory with more than $100 million in annual revenues.

The CEO of OK Stone has almost two decades of experience in the engineered stone industry. He began as a production engineer, later hired as a factory manager and eventually in the role of Managing Partner an an Industrial Investment fund, focusing on investments in engineered stone. He holds a Mechanical Engineering degree and an MBA.

The Chief Marketing Officer at OK Stone has more than 15 years of experience as a sales and marketing executive in the industry. He has worked for the top tier of engineered surfaces companies as well as a significant U.S.-based engineered stone company. He has recently been Sales and Marketing Director of a fully scaled Breton equipped factory, and was previously part of the founding team at a separate Breton factory, where he worked extensively in the U.S. market.

Ronald Max is COO at OK Stone. He has more than 35 years of experience in operations and finance. He has been involved in over $4 billion in real estate transactions and has extensive expertise in complicated ownership structures such as sale-leaseback financing, ground lease bifurcations and real estate securities offerings. In addition, he has experience in creating operating budgets, financial management and industrial real estate development for highly scaled enterprises.

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The QualityStocks Daily Newsletter brings you the latest company News and Profiles featuring the "Top Movers and Shakers" from the Small Cap Market each trading day. QualityStocks is committed to bring our subscribers Public companies in our Newsletter Section "Free of Charge" based on Percentage gained, Momentum, Press, and or Company Fundamentals.

Why do we spotlight companies for Free?
We Want To bring our subscribers the top movers in an unbiased setting.

"Homework Eliminates Mistakes"
Please never invest in a company anyone profiles unless you do the proper research and due diligence.

QualityStocks is compensated by the companies in The QS Company Corner. These companies will include a disclaimer with the amount and term of compensation.

Please consult the QualityStocks Market Basics Section on our site.

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